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Iranian Heart Journal، جلد ۱۹، شماره ۲، صفحات ۵۰-۵۶
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عنوان انگلیسی Functional and Structural Heart Conditions Associated With White-Coat Hypertension in Comparison With True Hypertension and Normal Blood Pressure States
چکیده انگلیسی مقاله Background: This study attempted to evaluate functional and structural cardiac states usingechocardiography in patients with white-coat hypertension in comparison with truehypertension and normotensive conditions.Methods: The study population consisted of 72 individuals, aged 25 to 75 years. The subjects wereassigned to 4 groups: white-coat hypertensives (n=20), controlled true hypertensives (n=20),uncontrolled true hypertensives (n=12), and a normotensive group (n=20). Whilst the 4 subgroups in the study exhibited a similar gender distribution, the normotensive subjects weresignificantly younger; however, there was no discrepancy in the mean age between the whitecoat hypertensive group and the other hypertensive subgroups. Univariate comparisons betweenthe functional and structural cardiac parameters of the white-coat hypertensives and the otherstudy groups revealed low deceleration time and E'-wave velocity and high E-wave velocityand left ventricular internal dimension indices compared with the other 2 hypertensive groups.Results: After adjustment for sex and age, the white-coat hypertensive group revealed differing resultsin 2 indices of E' wave velocity and interventricular septal thickness (IVST) when comparedwith the other three. A number of features were identified as the hallmarks of white-coathypertensives: specific functional and structural cardiac changes such as low IVST incomparison with the uncontrolled hypertensives; presence of diastolic dysfunction, which wasnot found in the normotensives; and greater cardiac mass than that in the normotensives, lessthan that in the uncontrolled hypertensives, but closer to that in the controlled hypertensives.Conclusions: Although the prognosis for patients with white-coat hypertension is not as grave as thatfor those with true hypertension, it is considerably worse than the prognosis among the normalpopulation.
کلیدواژه‌های انگلیسی مقاله Function, Structure, Heart, White-coat hypertension
نویسندگان مقاله Ahmad Mirdamadi |
Department of Cardiology, Najafabad Branch, Islamic Azad University, Najafabad, Isfahan, IR Iran

Mansoureh Safdari |
Department of Cardiology, Najafabad Branch , Islamic Azad University, Najafabad Isfahan, IR Iran

Mojgan Gharipour |
Candidate, Departments of Metabolic Syndrome, Isfahan Cardiovascular Research Center, Isfahan University of Medicine Sciences, Isfahan, IR Iran

Mohammad Garakyaraghi |
Heart Failure Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan , IR Iran

Ali Pourmoghadas |
Isfahan Cardiovascular Research center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, IR Iran.

نشانی اینترنتی http://journal.iha.org.ir/article_82814_9f47893e8d38d02a04b2eb66113753b2.pdf
فایل مقاله اشکال در دسترسی به فایل - ./files/site1/rds_journals/162/article-162-1423877.pdf
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