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Iranian Heart Journal، جلد ۱۹، شماره ۲، صفحات ۵۷-۶۴
عنوان فارسی
چکیده فارسی مقاله
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عنوان انگلیسی Value of Vitamin D Deficiency in Predicting the Severity of Coronary Artery Disease in Type 2 Diabetes
چکیده انگلیسی مقاله Background: The present study aimed to assess the relationship between vitamin D deficiency and theseverity of coronary artery disease (CAD) in a sample of Iranian diabetic patients.Methods: This cross-sectional study was performed on 169 consecutive diabetic patients suspected ofCAD. The severity of CAD was defined based the number of involved coronary vessels. Theserum vitamin D level was measured via immunoassay, and its serum level was categorized asnormal (>30 ng/mL), insufficient (20–30 ng/mL), mildly-to-moderately deficient (10–20ng/mL), and severely deficient (< 10 ng/mL).Results: There was no significant relationship between vitamin D deficiency and the number ofinvolved coronary vessels (P=0.423), and nor was there any difference in the serum level ofvitamin D in the individuals with CAD (24.84±18.53 ng/dL) and those without CAD(22.37±16.88 ng/mL) (P=0.409). Our multivariate logistic regression model showed thatvitamin D deficiency could not predict the presence of CAD (OR=0.963, 95% CI: 0.666 to1.392; P=0.842). Analysis of the area under the ROC curve indicated a low value for themeasurement of the vitamin D level in discriminating CAD from the normal coronary status(AUC=0.533, 95% CI: 0.437 to 0.629; P=0.496).Conclusions: Our study could not demonstrate a predictive role for vitamin D deficiency concerningthe severity of CAD in type 2 diabetes. Among the different CAD risk factors, smoking andopium use were significantly correlated with vitamin D deficiency.
کلیدواژه‌های انگلیسی مقاله Coronary artery disease, Vitamin D, Diabetes, Risk factor
نویسندگان مقاله Nima Akbarian |
Endocrinology and Metabolism Research Center, Institute of Basic and Clinical Physiology Sciences, Kerman University of Medical Sciences Kerman, IR Iran

Mohammad Masoomi |
Cardiovascular Research Center, Institute of Basic and Clinical Physiology Sciences, Kerman University of Medical Sciences Kerman, IR Iran

Maryam Sedaghat |
Physiology Research Center, Institute of Basic and Clinical Physiology Sciences, Kerman University of Medical Sciences, Kerman, IR Iran

Maryam Askari |
Gastroenterology and Hepatology Research Center, Institute of Basic and Clinical Physiology Sciences, Kerman University of Medical Sciences Kerman, IR Iran.

نشانی اینترنتی http://journal.iha.org.ir/article_82815_f4bc96036655c5fc5ef6f34b9873a843.pdf
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