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Iranian Heart Journal، جلد ۱۰، شماره ۴، صفحات ۴۵-۴۸
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عنوان انگلیسی AN 18-YEAR-OLD MAN WITH CARDIOMEGALY AND PERICARDIAL EFFUSION (CASE REPORT)
چکیده انگلیسی مقاله We present an 18-year-old male who sought medical attention due to exertional dyspnea of a few weeks' duration. His physical exam revealed an elevated jugular venous pressure, facial puffiness, muffled heart sounds, and mild lower extremity pitting edema.Chest X-ray showed cardiomegaly; and in echocardiography, huge intrapericardial masses with massive pericardial effusion were noted. The only noteworthy finding on abdominal ultrasonography and CT scan was the presence of ascites. The only abnormal laboratory results consisted of a hemoglobin level of 10.8 g/dl, a 1-hr ESR 77, CRP 34 mg/dl and LDH 771. Some 1500cc pericardial fluid was aspirated, and two multilobated creamy-brown masses with foci of necrosis and hemorrhage were excised.Microscopically, hypercellular sheets of malignant round cells were seen. Based on morphology, a diagnosis of high-grade round cell sarcoma was made. Immunohistochemical markers were negative for cytokeratin, CD 34, desmin, and smooth muscle actin, while positive reactivity was noted only for vimentin. Therefore, the cells were mesenchymal in origin with no vascular, skeletal, or smooth muscle differentiation and the final diagnosis was undifferentiated sarcoma.The patient was discharged in good clinical condition and underwent chemoradiation therapy.
کلیدواژه‌های انگلیسی مقاله CARDIAC TUMOR, UNDIFFERENTIATED SARCOMA, CARDIOMEGALY
نویسندگان مقاله Kambiz Mozaffari |
1Assistant Professor of Pathology, Shaheed Rajaie Cardiovascular Medical and Research Center (Corresponding author)

Farzad Yazdani Biucki |
2Assistant Professor of Pathology, Tehran University of Medical Sciences

Ahmad Amin |
3Assistant Professor of Cardiology, Shaheed Rajaie Cardiovascular Medical and Research Center

Katayoun Rahmatabadi |
4Clinical and Anatomical Pathologist, Surgical Pathology and IHC Dept, Iranian Blood Transfusion Organization

نشانی اینترنتی http://journal.iha.org.ir/article_83814_17fc8c07881371fb598490756530f640.pdf
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