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Iranian Heart Journal، جلد ۱۰، شماره ۱، صفحات ۴۰-۴۷
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عنوان انگلیسی C - REACTIVE PROTEIN AND CORONARY CALCIUM SCORE ASSOCIATION IN CORONARY ARTERY DISEASE
چکیده انگلیسی مقاله Objectives- Both high-sensitivity C-reactive protein (hs-CRP) and spiral computed tomography coronary artery calcium score are valid markers of cardiovascular risk. It is unknown whether hs-CRP is a marker of atherosclerotic burden or whether it reflects a process leading to acute coronary events.Methods- We studied the association of high-sensitivity C-reactive protein and coronary calcium score in 143 patients that were candidates for coronary artery bypass graft surgery.Results- In our cross sectional study we found no significant association between high-sensitivity C-reactive protein and coronary calcium score in bivariants (p=0.162) and multivariable (p=0.062) analysis, but in patients who did not use statins, this association was significant and positive in bivariant (p=0.001) and in multivariate analysis this association was negative and significant (p=0.008).Conclusion- High-sensitivity C-reactive protein was not associated with coronary calcium score. The relation between C-reactive protein and clinical events might not be related to atherosclerotic burden. Measures of inflammation, such as C-reactive protein, and indices of atherosclerosis, such as coronary calcium score, are likely to provide distinct information regarding cardiovascular risk.
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نویسندگان مقاله A HOSSEINSABET |


BAHRAM MOHEBI |
DEPARTMENT OF CARDIOLOGY, SHAHEED RAJAIE CARDIOVASCULAR, MEDICAL AND RESEARCH CENTER, TEHAN, IRAN

AHMAD MOHEBI |


A.R. ALMASI |


نشانی اینترنتی http://journal.iha.org.ir/article_83731_8bf7f447aa7d92c2927e60b778850050.pdf
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