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JCR 2016
جستجوی مقالات
سه شنبه 25 آذر 1404
Middle East Journal of Cancer
، جلد ۱۰، شماره ۲، صفحات ۱۳۹-۱۵۵
عنوان فارسی
چکیده فارسی مقاله
کلیدواژههای فارسی مقاله
عنوان انگلیسی
Economic Burden of Prostate Cancer in Iran: Measuring Costs and Quality of Life
چکیده انگلیسی مقاله
Background: Prostate cancer (PCa) is the third most diagnosed cancer among men in Iran with approximately 4200 new cases in 2015. Considering the rapid growth of cancer diagnosis, this study aims to investigate the economic burden of PCa patients and their health-related quality of life (HRQoL) Methods: A retrospective survey was conducted on 500 registered patients to discover the pattern of care and distribution of patients in the main treatment categories. In the next step, a multi-center survey of the patients under treatment was conducted. The objective of this survey was to estimate direct medical costs (DMC), non-medical costs, and productivity losses for patients and family members. HRQoL was measured by the Functional Assessment of Cancer Therapy–Prostate questionnaire. Results: Despite high age of patients (72±9.25 years), only 53.3% of them were retired or disabled. The largest proportion of patients (54.3%) received medicinal or surgical hormone therapy. Radical prostatectomy was the main treatment for 31.7% of patients, 10.2% received radiation therapy, and 3.8% underwent chemotherapy. DMC for incident population was approximately 12.5 million US dollars/year, and the highest average cost per capita belonged to chemotherapy patients. Unpredictably, productivity loss was nearly as much as direct cost. The mean score for HRQoL was 0.62±0.16 for all patients. Orchiectomy group had the lowest HRQoL score (0.55±0.16). Chemotherapy patients suffered the worst scores in the physical well-being subscale (0.47±0.24). Hormone therapy patients had the least scores in the prostate-specific subscale (0.50±0.18). Conclusion: The economic burden of PCa is estimated approximately 25.8 million US dollars per year for incident population. When we refer to the high proportion of patients diagnosed in advanced state of the disease and higher per capita cost for these patients, policy makers should promote screening strategies to control health care costs and to increase both life expectancy and HRQoL.
کلیدواژههای انگلیسی مقاله
نویسندگان مقاله
Mohamad Javad Foroughi Moghadam |
Department of Pharmacoeconomics and Pharmaceutical Management, School of Pharmacy, Shahid Beheshti University of Medical Sciences, Tehran
Mohsen Ayati |
Uro-Oncology Research Center, Tehran University of Medical Sciences, Tehran
Maryam Rangchian |
Department of Pharmacoeconomics and Pharmaceutical Management, School of Pharmacy, Shahid Beheshti University of Medical Sciences, Tehran
Gholamreza Pourmand |
Urology Research Center, Sina Hospital, Tehran University of Medical Sciences, Tehran
Peiman Haddad |
Radiation Oncology Research Center, Cancer Institute, Tehran University of Medical Sciences, Tehran
Alireza Nikoofar |
Department of Radiation Oncology, Iran University of Medical Sciences, Tehran
Hamidreza Rezvani |
Department of Medical Oncology, Taleghani Hospital, Shahid Beheshti University of Medical Sciences, Tehran
Seyed Jalil Hosseini |
Department of Urology, Shohada-e-Tajrish Hospital and Urology-Nephrology Research Center, Shahid Beheshti University of Medical Sciences, Tehran
Jamshid Salamzadeh |
Department of Pharmacoeconomics and Pharmaceutical Management, School of Pharmacy, Shahid Beheshti University of Medical Sciences, Tehran
Hamid Reza Rasekh |
Department of Pharmacoeconomics and Pharmaceutical Management, School of Pharmacy, Shahid Beheshti University of Medical Sciences, Tehran
نشانی اینترنتی
http://mejc.sums.ac.ir/article_44864_b7fb7b29097fff08d35076573f5f99b6.pdf
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اشکال در دسترسی به فایل - ./files/site1/rds_journals/181/article-181-1495833.pdf
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