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Iranian Journal of Medical Physics، جلد ۱۵، شماره Special Issue-۱۲th. Iranian Congress of Medical Physics، صفحات ۲۵-۲۵
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عنوان انگلیسی Automatic Segmentation of the Gross Tumor Volume in Prostate Carcinoma Using Fuzzy Clustering in Gallium-68 PSMA PET/CT Scan
چکیده انگلیسی مقاله Introduction: Modern radiotherapy (RT) techniques allow a highly precise deposition of the radiation dose in tumor. So, high conformal tumor doses can be reached while sparing critical organs at risk. Materials and Methods: This study was conducted in three phases. In the first phase; Fourteen patients with primary or recurrent prostate cancer receive Gallium-68 PSMA PET/CT planned 3D conformal or intensity modulated radio therapy. In the second phase; fuzzy clustering method to definition the gross volume tumor in prostate. In the next phase; increasing the dose in the tumor according to the functional and molecular information assessed by combined PET/CT imaging and result of clustering. Result: The mean standard uptake value (Suv) was 6.2 in the lesion of the prostate. To administer 75.6Gy to the entire prostate with a boost dose to 84Gy, was feasible. Conclusion: The additional of the simultaneous integrated boost(SIB) was associated with greater control but not toxicity.
کلیدواژه‌های انگلیسی مقاله Radiotherapy, Gallium-68, PET/CT
نویسندگان مقاله | Khadijeh Bamneshin
Iran University of Medical Science, Tehran, Iran


| Ahmad Bitarafan rajabi
Rajaie Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, IR


| Seied Rabi Mahdavi
Medical Physics Department, Tehran University of Medical Science, Tehran, Iran


| Parham Geramifar
Asisstant Professor, Tehran University of Medical Sciences, Tehran, Iran
نشانی اینترنتی http://ijmp.mums.ac.ir/article_11880.html
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