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مجله حکیم سیداسماعیل جرجانی، جلد ۷، شماره ۱، صفحات ۰-۰
عنوان فارسی
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عنوان انگلیسی The preventive effect of Chlorhexidine mouthwash on alpha-hemolytic Streptococci and Staphylococcus aureus
چکیده انگلیسی مقاله Background and objectives: The association of oral micro-organisms with infectious diseases such as bacterial endocarditis is a concern in dentistry. Bacterial endocarditis is a serious disease with a mortality rate of 40%. The present study was conducted to investigate the effect of using chlorhexidine mouthwash on concentrations of some groups of bacteria in gingival sulcus, which is the main contact point of oral flora with circulating blood during scaling. ­­­ Methods: In this Randomized controlled clinical trial, participants were selected among referrals to the department of gingival diseases of Yazd dental school. Participants underwent determining plaque index and after scaling, sampling of the buccal and lingual gingival groove of mandibular central and lateral teeth was performed by paper with walking movement. Results: participants were 53 patients who divided into two groups. Group A consisted of 27 patients (15 women and 12 men) ranging in age from 21 to 54 years mean of 35) who used 50 mL chlorhexidine mouthwash and Group B consisted of 26 patients (13 females and 13 males) ranging in age from 19 to 51 years old with a mean of 35.76 who used 50 mL normal saline before scaling. Study groups were not significantly different in terms of age, sex and plaque index. (P-values= 0.755, 0.348 and 0.708) Mann Whitney-Wilcoxon test compared the counted values of Streptococcus viridance and Staphylococcus aureus in control group was significantly higher than the study group. (P-value = 0.000) Conclusion: according to the results of our study chlorhexidine mouthwash prior to scaling teeth significantly reduced Streptococcus viridance and Staphylococcus aureus colony counts and could be recommended as a complementary agent for antibiotic prophylaxis in high risk patients prone to endocarditis, or as the only agent in moderate risk cardiac patients that antibiotic prophylaxis does not been used.
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نویسندگان مقاله | Mohammad-Hassan akhavan karbassi
Assistant Professor, Department of Oral Medicine, Shahid Sadoughi University of Medical Science, Yazd, Iran


| fatemeh owlia
Assistant Professor, Department of Oral Medicine, Shahid Sadoughi University of Medical Science, Yazd, Iran


| henghameh zandi
Assistant Professor, Department of Medical Microbiology, Shahid Sadoughi University of Medical Science, Yazd, Iran


| samira hajimaghsoodi
Assistant Professor, Department of Oral Medicine, Shahid Sadoughi University of Medical Science, Yazd, Iran
نشانی اینترنتی http://goums.ac.ir/jorjanijournal/browse.php?a_code=A-10-505-1&slc_lang=en&sid=1
فایل مقاله اشکال در دسترسی به فایل - ./files/site1/rds_journals/323/article-323-1566951.htm
کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده علوم پایه پزشکی
نوع مقاله منتشر شده تحقیقی
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