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Iranian Journal of Medical Sciences، جلد ۳۸، شماره June Supplement ۲۰۱۳، صفحات ۱۹۵-۱۹۷
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عنوان انگلیسی Reactivation of Cytomegalovirus in a Patient with Stevens-Johnson Syndrome-Toxic Epidermal Necrolysis
چکیده انگلیسی مقاله Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are severe adverse cutaneous reactions to drugs. We describe the case of a 19 year old patient with SJS/TEN overlap syndrome, who developed severe interstitial pneumonia after she had received antiepileptic drugs. A cytomegalovirus infection was diagnosed by Real Time Polymerase Chain Reaction (RT-PCR) detection on Bronchoalveolar lavage. Based on observations on biological data, temporal relationship, and clinical features, it could be inferred that the reactivation of cytomegalovirus with viral replication can predispose a person to TEN-SJS. We discuss here, in the light of the current literature, the probable association between drug-induced SJS-TEN and fulminant reactivation of cytomegalovirus.
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نویسندگان مقاله Mohamed Rida Tagajdid |
Laboratory of Virology, Mohamed V Souissi University, Mohamed V Military Teaching Hospital, Rabat, BP, Morocco

Taoufik Doblali |
Laboratory of Virology, Mohamed V Souissi University, Mohamed V Military Teaching Hospital, Rabat, BP, Morocco

Hicham Elannaz |
Laboratory of Virology, Mohamed V Souissi University, Mohamed V Military Teaching Hospital, Rabat, BP, Morocco

Salaheddine Hammi |
Department of Internal Medicine, Mohamed V Military Teaching Hospital, Rabat, BP, Morocco

Bouchra Belfequih |
Laboratory of Virology, Mohamed V Souissi University, Mohamed V Military Teaching Hospital, Rabat, BP, Morocco

Saâd Mrani |
Laboratory of Virology, Mohamed V Souissi University, Mohamed V Military Teaching Hospital, Rabat, BP, Morocco

نشانی اینترنتی http://ijms.sums.ac.ir/article_44105_14a07299e127071e03fe58fd7ea2f1b5.pdf
فایل مقاله اشکال در دسترسی به فایل - ./files/site1/rds_journals/147/article-147-1611526.pdf
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