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Iranian Journal of Otorhinolaryngology، جلد ۳۱، شماره ۴، صفحات ۲۰۹-۲۱۵
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عنوان انگلیسی Correlation between Allergic Rhinitis and Otitis Media with Effusion
چکیده انگلیسی مقاله Introduction: Otitis media with effusion (OME) is prevalent among children in such a way that it is the most common cause of hearing loss and surgery in childhood. Immunoglobulin E (IgE) mediated hypersensitivity has been proposed as a causative factor in the development of OME; however, there has been contrasting data in this regard. Therefore, the present study aimed to detect the possibilities of interconnection. Materials and Methods: In this study, 37 OME children were selected as the case group and 52 children were randomly chosen as the control group. Allergic rhinitis prevalence, serum total IgE concentration, serum eosinophil count, and nasal scraping cytology were evaluated in all the children. Furthermore, the skin prick test was performed in the OME group and suspected allergic rhinitis patients in the control group. Results: Allergic rhinitis prevalence was notably higher among OME patients than in the control group (P=0.01). There were no remarkable differences in eosinophil counts and serum IgE concentrations in the two groups. Nasal smear eosinophils did not show any significant difference between the two groups; however, Appreciable difference was observed in the allergic rhinitis patients, compared to other OME patients (P=0.004). Conclusion: There may be a correlation between allergic rhinitis and development of OME. Therefore, it seems reasonable to examine allergic rhinitis patients for OME.
کلیدواژه‌های انگلیسی مقاله Allergic Rhinitis, Nasal mucosa, Otitis media with effusion
نویسندگان مقاله | Mohammad Reza Sharifian
Department of Otorhinolaryngology-Head & Neck Surgery, Mashhad University of Medical Sciences, Mashhad, Iran.


| Mahmoud Mahmoudi
Immunology Research Centre, Imam Reza Hospital, Faculty of Medicine, Mashhad University of Medical


| Babak Pourmomenarabi
Department of Otorhinolaryngology-Head & Neck Surgery, Mashhad University of Medical Sciences, Mashhad, Iran.


| Mohammad Reza Keramati
Cancer Molecular Pathology Research Center, Imam Reza Hospital, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
نشانی اینترنتی http://ijorl.mums.ac.ir/article_13017.html
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