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Journal of Dentomaxillofacil Radiology, Pathology and Surgery، جلد ۷، شماره ۳، صفحات ۳-۳
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عنوان انگلیسی Comparing Serum Zinc Level between Patients with Recurrent Herpes Labialis and Healthy People
چکیده انگلیسی مقاله Background Recurrent herpes labialis is the most common infective vesiculoulcerative lesion. Reportedly, zinc has preventive and therapeutic effects on ulcer healing. The purpose of this article is to compare the level of zinc between people with recurrent herpes labialis and healthy people. Methods  This descriptive cross-sectional study was conducted on 85 subjects, including 43 patients with recurrent herpes labialis and 42 healthy individuals. The study samples were selected from the patients referring to the Shiraz School of Dentistry with the history of herpes labialis approved by the oral and maxillofacial specialist in 2018. Healthy individuals were selected from the patients who visited the School of Dentistry for dental examinations in 2018. They had no systemic and immunological disease, the recurrent oral lesion, or under supplementary medication. Then, blood samples were taken from the samples, and their serum zinc level was measured. The Chi-square test was used to compare the qualitative relationships and the Independent t test to compare the quantitative relationships.  Serum zinc level, the number of relapses, and recovery rates were obtained to explore the relationships between quantitative factors. All analyses were performed in SPSS. Results Serum zinc level did not show a significant statistical difference between the healthy and patient groups (P > 0.05). Also, the zinc level was not correlated with age, sex, or the frequency of relapse (P> 0.05). However, in the patient's group, there was a significant relationship between the zinc level and recovery period. The lower the serum zinc level, the higher would be the duration of recovery (P < 0.05). Conclusion Zinc deficiency is a risk factor for prolongation of the recovery period of herpes labialis. Therefore, we recommend the evaluation of serum zinc level in people with recurrent herpes labialis and subsequent administration of zinc if necessary.
کلیدواژه‌های انگلیسی مقاله Zinc, Serum, Herpes labialis
نویسندگان مقاله | Zahra Ranjbar
Department of Oral and Maxillofacial Medicine, Oral and Dental Disease Research Center, School of Dentistry, Shiraz University of Medical Sciences, Shiraz, Iran.


| Maryam Zahed
Department of Oral and Maxillofacial Medicine, Oral and Dental Disease Research Center, School of Dentistry, Shiraz University of Medical Sciences, Shiraz, Iran.


| Zahra Shirmardan
Undergraduate Student, School of Dentistry, Shiraz University of Medical Sciences, Shiraz, Iran.
نشانی اینترنتی http://3dj.gums.ac.ir/browse.php?a_code=A-10-201-1&slc_lang=en&sid=1
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