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International Journal of Fertility and Sterility، جلد ۷، شماره ۳، صفحات ۹۷-۹۷
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عنوان انگلیسی P-159: Women's Infertility and Polycystic Ovarian Syndrome, Concepts and Treatment
چکیده انگلیسی مقاله Background: Polycystic ovarian syndrome (PCOS) is a medical condition that affects women's menstrual cycles, fertility, hormone levels, and physical appearance. PCOS is thought to be one of the leading causes of female infertility, and is the reason of more than 75% of cases of anovulatory infertility. Materials and Methods: In this article, we review the different aspects of PCOS including genetic biasis and treatment. Results: The mechanism of anovulation is uncertain, but there is evidence that arrested antral follicle development is associated with the abnormal endocrine profile, in particular the interaction of insulin and LH on granulosa cell differentiation. Clinical evidence indicates that polycystic ovary syndrome has a heritable basis, at least in part, which could result from a genetic etiology, epigenetic changes, or an admixture of the two causes. Conclusion: Although, there is no cure for PCOS, but controlling it lowers the PCOS risks of infertility, miscarriages, diabetes, heart disease, and uterine cancer. Management of infertility in polycystic ovary syndrome includes lifestyle modification as well as assisted reproductive technology such as ovulation induction, oocyte release triggering and surgery.
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نشانی اینترنتی http://ijfs.ir/journal/article/abstract/3620
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