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International Journal of Radiation Research، جلد ۱۳، شماره ۳، صفحات ۲۴۳-۲۴۹
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عنوان انگلیسی Dose response evaluation of a low density anoxic polymer gel dosimeter using MRI
چکیده انگلیسی مقاله Background: The human body contains of different tissues and cavities with different physical and radiological properties. Most important among these are tissues and cavities that are radiologically different from water, including lungs, sinuses and bones. Gel dosimetry provides a unique feature to display dose distributions occurring in clinical radiation therapy in three dimensions. Materials and Methods: The low density polymer gel dosimeter is composed of 12% gelatin, 5% methacrylic acid, 0.15% sodium dodecyl sulfate, 10 mM THPC, and approximately 83% ultrapure deionized water. Post- preparation irradiation time for all samples was 5 hr. The time between irradiation and scanning for all gels experiments was 18 hr. The gel dosimeters were imaged using a 1.5 T clinical MRI scanner in a transmitter/receiver head coil. Results: There was a linear correlation between the doses and R2 responses from 0 to 12 Gy. However, above the 14 Gy probably due to saturation and or consumption of the monomers the dose response was reduced. The low-density gels had a mass density between 0.35 and 0.45 g.cm-3 and the CT values of about -650 to -750 Hounsfield units. These values are close to those of the normal human lung tissue, which ranges from -770 to -875 Hounsfield units. Conclusion: Increasing the gel temperature during rotation in the household mixer and probably reactions between the gelatin-free radicals and monomers led to a higher R2-background response.
کلیدواژه‌های انگلیسی مقاله Low density polymer gel dosimetry, radiation therapy, MRI
نویسندگان مقاله m غلامی | m. gholami
department of medical physics and medical engineering, school of medicine, isfahan university of medical sciences, isfahan, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی اصفهان (Isfahan university of medical sciences)

d شهبازی گهرویی | d shahbazi gahrouei
department of medical physics and medical engineering, school of medicine, isfahan university of medical sciences, isfahan, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی اصفهان (Isfahan university of medical sciences)

t الهویردی پورفلاح | t allahverdi pourfallah
department of biophysics and biochemistry, school of medicine, mazandaran university of medical sciences, sari, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی مازندران (Mazandaran university of medical sciences)

نشانی اینترنتی http://www.ijrr.com/browse.php?a_code=A-10-1-568&slc_lang=en&sid=en
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کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده Radiation Biology
نوع مقاله منتشر شده تحقیق بدیع
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