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International Journal of Radiation Research، جلد ۱۳، شماره ۱، صفحات ۳۹-۴۳
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عنوان انگلیسی The influence of respiratory motion on dose distribution of 3D-CRT and IMRT- A simulation study
چکیده انگلیسی مقاله Background: 3DCRT (three-dimensional conformal radiotherapy) and IMRT (intensity-modulated radiotherapy) has provided us with tools to delineate the radiation dose distribution of tumor targets. However, the precision of radiation can be compromised by respiratory motion, which usually limits the geometric and dosimetric accuracy of radiotherapy. The purpose of this study is to evaluate the impact of respiratory motion on dose distributions of 3D-CRT and dynamic IMRT by simulating the respiratory motion, and provide suggestions to optimize treatment planning. Materials and Methods: American Sun Nuclear Mapcheck 2D-ARRAY was placed on a moving platform to simulate the respiratory motion. The dose distributions were measured with a Sun Nuclear Mapcheck 2D-ARRAY on the moving platform. The motion cycle was 3.5s, the amplitude was ±3mm, ±5mm, ±10mm, ±15mm. Dosimetric distribution between 3DCRT and IMRT plans were contrasted byγ-passing rate analysis. SPSS 13.0 software was used for data processing and analysis. Results: The respiratory motion could blur the target dose distribution of 3D-CRT and IMRT. The pass rate (3% 3mm) in 3DCRT was larger than that in IMRT. The Mapcheck software reflected that, the respiratory motion largely affected the marginal dose distribution of 3D-CRT, while affected the whole target volumes of IMRT. Conclusions: Respiratory motion has a greater impact on the dose distribution of IMRT than on 3D-CRT. As for tumors with large motion amplitude, it is advisable to use 3DCRT rather than IMRT techniques.
کلیدواژه‌های انگلیسی مقاله Respiratory motion, 3DCRT, DIMRT, Dose distribution
نویسندگان مقاله r چنگ li | r chang li
cancer center, renmin hospital of wuhan university, wuhan 430060, china


c yu xin | c yu xin
cancer center, renmin hospital of wuhan university, wuhan 430060, china


w lu zhou | w lu zhou
cancer center, renmin hospital of wuhan university, wuhan 430060, china


wu bing | wu bing
cancer center, renmin hospital of wuhan university, wuhan 430060, china


s qi بین | s qi bin
cancer center, renmin hospital of wuhan university, wuhan 430060, china
نشانی اینترنتی http://www.ijrr.com/browse.php?a_code=A-10-1-539&slc_lang=en&sid=en
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کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده Radiation Biology
نوع مقاله منتشر شده تحقیق بدیع
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