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International Journal of Radiation Research، جلد ۱۲، شماره ۴، صفحات ۳۱۱-۳۱۷
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عنوان انگلیسی Dosimetric comparison of two different whole brain radiotherapy techniques in patients with brain metastases: How to decrease lens dose?
چکیده انگلیسی مقاله Background: Palliative whole brain radiotherapy (WBRT) has been the standard treatment for brain metastases. Ionizing radiation is known to be one of the most potent cataractogenic agents. We aimed to evaluate two different radiotherapy techniques with respect to the doses received by the organs at risk (OAR) in patients with brain metastasis who undergone WBRT. Materials and Methods: Ten consecutive patients with brain metastasis were included. For each patient, two different treatment plans were created for whole brain. Helmet-field (HF) (anterior border was 2 cm posterior to lens, inferior border was the bottom of C2 vertebra) and classical technique with collimation (CT) (anterior border was defined as skin fall off, inferior border was the bottom of cranial base) were generated for all patients. Two techniques were compared with respect to the doses received by the OAR including bilateral lenses, optic nerves and eye-balls, the dose homogeneity index (DHI), and the monitor unit counts (MU) required for the treatment. Student-t test was used for statistical analysis. Results: There was no difference between two techniques in terms of both DHI (p: 0.182) and MU counts (p: 0.167). The maximum and mean doses received by the right lens, left lens and right eye-ball were significantly reduced with CT (p values for maximum doses 0.007, 0.012 and 0.010 for median doses 0.027, 0.046 and 0.002 respectively). Conclusion: CT was found to be more advantageous, with respect to the lens doses in addition the dose received by the right eye-ball during WBRT.
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نویسندگان مقاله g yavas | g. yavas
selcuk university, department of radiation oncology, konya, turkey


c yavas | c. yavas
konya training and research hospital, department of radiation oncology, konya, turkey


o v gul | o v gul
medipol university, department of radiation oncology, istanbul, turkey


h acar | h. acar
medipol university, department of radiation oncology, istanbul, turkey


o عطا | o. ata
selcuk university, department of medical oncology, konya, turkey
نشانی اینترنتی http://www.ijrr.com/browse.php?a_code=A-10-1-521&slc_lang=en&sid=en
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کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده Radiation Biology
نوع مقاله منتشر شده تحقیق بدیع
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