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International Journal of Radiation Research، جلد ۱۲، شماره ۴، صفحات ۳۴۳-۳۴۶
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عنوان انگلیسی Assessment of molybdenum breakthrough levels in molybdenum-99/technetium-99m generators: One year experience at NIMRA Jamshoro Pakistan
چکیده انگلیسی مقاله Background: Technetium-99m radioisotope is the backbone of any nuclear medicine institute. This radioisotope is acquired by the elution of Molybdenum-99/Technetium-99m generator which emits 141 keV gamma ray and having 6.04 hour half-life. Occasionally the contents of Molybdenum-99 may mix up with elute, which may affect image quality and patients may receive higher doses than recommended. This study was initiated to check and evaluate the contamination of Molybdenum-99 in Molybdenum-99/Technetium-99m generators used at Nuclear Institute of Medicine and Radiotherapy (NIMRA) Jamshoro Pakistan before its administration to patients for diagnostic procedures. Materials and Methods: The Molybdenum-99 impurity in Technetium-99m elute for 50 generators was studied during the year 2012. The measurements were made using dose calibrator and a standard canister at the time of first elution of the generators. The dose calibrator displays result after executing various steps in a sequence. Due to some production process error or any mechanical fault high activity of Molybdenum-99 was recorded and removed with decrease in Technetium-99m yield. Results: The most of eluted generators (90%) contained 10% of molybdenum breakthrough of the permissible limit (P < 0.05). The high activity of Molybdenum-99 was recorded in only 6% of the generator and removed by using standard methods with some reduced Technetium-99m activity. Conclusion: The molybdenum breakthrough was according to recommended standards in most of the generators. The removal of high contents of Molybdenum-99 enabled the institute to continue routine imaging services by improved image quality and reduction in radiation dose to the patients.
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نویسندگان مقاله سید علی memon | s a memon
nuclear institute of medicine and radiotherapy nimra jamshoro, pakistan


نجف علی لاغری | n a laghari
nuclear institute of medicine and radiotherapy nimra jamshoro, pakistan


سید تقی اقبال قریشی | s t qureshi
university of sindh, jamshoro, pakistan


f مهدی | f. mehdi
nuclear institute of medicine and radiotherapy nimra jamshoro, pakistan
نشانی اینترنتی http://www.ijrr.com/browse.php?a_code=A-10-1-526&slc_lang=en&sid=en
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کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده Radiation Biology
نوع مقاله منتشر شده تحقیق بدیع
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