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International Journal of Radiation Research، جلد ۱۲، شماره ۲، صفحات ۱۵۱-۱۶۰
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عنوان انگلیسی Effect of uniform magnetic field on dose distribution in the breast radiotherapy
چکیده انگلیسی مقاله Background: To reduce the dose to normal tissues surrounding the treated breast, a uniform magnetic field was used within a humanoid phantom in breast radiotherapy. Materials and Methods: Monte Carlo simulations were performed with GEANT4, irradiating humanoid phantoms in a magnetic field. To reconstruct phantoms, computed tomography (CT) data slices of four patients were used for the Monte Carlo simulations. All of them had left breast cancer either or not mastectomy. In the simulations, the planning and methods of chest wall irradiation were similar to the actual clinical planning. Results: Utilizing magnetic field will help to produce uniform dose distribution to the breast with a sharp dose-volume histogram (DVH) curve for the planning target volume (PTV), however, for the ipsilateral lung and chest wall skin the mean dose was reduced by a mean of 16% and 12% at 1.5 T, and 9% and 7% at 3 T, respectively. The magnetic field was shown to restrict the lateral spread of secondary electrons to the contralateral organs, resulting in significient dose reductions to the contralateral breast (CB) and contralateral chest wall skin (CCWS) by a mean (range) of 28% (21-37%) and 58% (44-75%) at 1.5 T, and 48% (32-81) and 66% (54-73%) at 3 T, respectively. Conclusion: The simulations established that the magnetic field can reduce the dose to the internal and contralateral tissues and increase it to the PTV with sharper edge DVH curve.
کلیدواژه‌های انگلیسی مقاله ERE, magnetic field, breast, GEANT4
نویسندگان مقاله آرتا دخت اسماعیلی | a d esmaeeli
department of medical radiation engineering, science and research branch, islamic azad university, tehran, iran

سازمان اصلی تایید شده: دانشگاه آزاد اسلامی علوم و تحقیقات (Islamic azad university science and research branch)

m پولادیان | m. pouladian
department of medical radiation engineering, science and research branch, islamic azad university, tehran, iran

سازمان اصلی تایید شده: دانشگاه آزاد اسلامی علوم و تحقیقات (Islamic azad university science and research branch)

علی اصغر منفرد | a s monfared
department of medical physics, babol university of medical sciences, babol, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی بابل (Babol university of medical sciences)

سیدرضا مهدوی | s r mahdavi
department of medical physics, tehran university of medical sciences, tehran, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

d مسلمی | d. moslemi
department of radiation oncology, babol university of medical sciences, babol, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی بابل (Babol university of medical sciences)

نشانی اینترنتی http://www.ijrr.com/browse.php?a_code=A-10-1-500&slc_lang=en&sid=en
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کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده Radiation Biology
نوع مقاله منتشر شده تحقیق بدیع
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