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International Journal of Radiation Research، جلد ۹، شماره ۴، صفحات ۲۰۹-۲۱۹
عنوان فارسی
چکیده فارسی مقاله
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عنوان انگلیسی FDG-PET/MRI fused data sets for the detection of liver metastases in patients undergoing systemic anticancer treatment
چکیده انگلیسی مقاله Background: To retrospectively describe imaging characteristics of liver metastases on fused FDG-PET/ MRI data sets and to compare the diagnostic accuracy of MRI and fused FDG-PET/MRI data sets for the detection of liver metastases in patients undergoing systemic anticancer treatment. Materials and Methods: 43 oncological patients (mean age: 56+/- 11 years) were investigated by FDG-PET/CT and liver MRI. FDG-PET data from PET/CT scans were fused with MRI. 556 lesions were evaluated. 5 different evaluation algorithms were used for FDG-PET/ MRI evaluation. The sensitivity, specifity, PPV, NPV and accuracy of MRI and FDG-PET/MRI data for the detection of liver metastases were calculated. A mean follow-up of 647 days served as reference standard. McNemar’s test was used to test for statistically significant differences between MRI and FDG-PET/MRI (p< 0.5). Results: The sensitivity, specificity, PPV, NPV and accuracy of MRI for the detection of liver metastases were 86%, 81%, 97%, 47%, and 85% and 50%, 100%, 100%, 22%, and 56%, for FDGPET/ MRI. FDG-PET/MRI was significantly less accurate than MRI alone (p<.001). Conclusion: In opposite to patients before systemic anticancer therapy the fusion of FDG-PET data with liver MRI cannot be recommended for the detection of liver metastases in patients undergoing systemic oncological therapy. Iran. J. Radiat. Res., 2012 9(4): 209-219
کلیدواژه‌های انگلیسی مقاله PET/MRI, PET/CT, liver MRI, liver metastases, hybrid imaging
نویسندگان مقاله t a heusner | t a heusner
university of dusseldorf, medical faculty, department of diagnostic and interventional radiology, d-40225 dusseldorf, germany


c mikat | c. mikat
university of duisburg-essen, medical faculty, department of diagnostic and interventional radiology and neuroradiology, d-45147 essen, germany


s hahn | s. hahn
university of duisburg-essen, medical faculty, department of diagnostic and interventional radiology and neuroradiology, d-45147 essen, germany


j altenbernd | j. altenbernd
university of duisburg-essen, medical faculty, department of diagnostic and interventional radiology and neuroradiology, d-45147 essen, germany


a stahl | a. stahl
university of duisburg- essen, medical faculty, department of nuclear medicine, d-45147 essen, germany


a bockisch | a. bockisch
university of duisburg- essen, medical faculty, department of nuclear medicine, d-45147 essen, germany


m forsting | m. forsting
university of duisburg-essen, medical faculty, department of diagnostic and interventional radiology and neuroradiology, d-45147 essen, germany


g antoch | g. antoch
university of dusseldorf, medical faculty, department of diagnostic and interventional radiology, d-40225 dusseldorf, germany
نشانی اینترنتی http://www.ijrr.com/browse.php?a_code=A-10-1-405&slc_lang=en&sid=en
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کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده Radiation Biology
نوع مقاله منتشر شده تحقیق بدیع
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