این سایت در حال حاضر پشتیبانی نمی شود و امکان دارد داده های نشریات بروز نباشند
International Journal of Radiation Research، جلد ۷، شماره ۲، صفحات ۶۹-۷۷
عنوان فارسی
چکیده فارسی مقاله
کلیدواژه‌های فارسی مقاله
عنوان انگلیسی Modification of 10 cGy neutron or gamma-rays induced chromosomal damages by hyperthermia: an in vitro study
چکیده انگلیسی مقاله Background: To evaluate the effects of hyperthermia (HT) on the frequency of chromosomal aberrations induced by a low dose of neutron or γ-rays in human peripheral blood lymphocytes. Materials and Methods: Blood samples were exposed to HT (41.5°C for 30 and 60min, 43°C for 15 and 30min), 10 cGy neutron or γ-rays, HT + neutron/γ, and neutron/γ + HT. After standard cell culture, harvesting, fixation and staining, the chromosomal damages were scored in metaphase plates. Results: HT alone at 41.5°C did not induce chromatid or chromosome aberrations, however, the frequency of damages was significantly higher at 43°C (P< 0.05). Furthermore, the chromosomal damages was significantly different when cells were irradiated with neutron or γ-rays alone (P< 0.01). HT 1 hr post neutron/γ irradiation significantly induced higher chromosome damages in comparison to HT 1 hr before irradiation (P< 0.05). The chromosomal damages were remarkably higher when cells were irradiated with neutron then heated at 43°C for 30 min. Conclusion: Since increasing frequency of chromosome damages increases probability of cell death, application of HT after neutron irradiation (instead of X– or γ- rays) might be considered as a procedure for cells killing in radiotherapy. Iran. J. Radiat. Res., 2009 7 (2): 69-77
کلیدواژه‌های انگلیسی مقاله
نویسندگان مقاله d فاتحی | d. fatehi
department of medical physics, faculty of medicine, shahrekord university of medical sciences, shahrekord, iran


h مزدارانی | h. mozdarani
department of medical genetics, faculty of medical sciences, tarbiat modares university,tehran, iran

سازمان اصلی تایید شده: دانشگاه تربیت مدرس (Tarbiat modares university)

نشانی اینترنتی http://www.ijrr.com/browse.php?a_code=A-10-1-320&slc_lang=en&sid=en
فایل مقاله فایلی برای مقاله ذخیره نشده است
کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده Radiation Biology
نوع مقاله منتشر شده تحقیق بدیع
برگشت به: صفحه اول پایگاه   |   نسخه مرتبط   |   نشریه مرتبط   |   فهرست نشریات