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International Journal of Radiation Research، جلد ۷، شماره ۱، صفحات ۴۹-۵۶
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عنوان انگلیسی Verifying the accuracy of dose distribution in Gamma Knife unit in presence of inhomogeneities using PAGAT polymer gel dosimeter and MC simulation
چکیده انگلیسی مقاله Background: Polymer gel dosimetry is still the only dosimetry method for direct measuring of threedimensional dose distributions. MRI Polymer gel dosimeters are tissue equivalent and can act as a phantom material. In this study the obtained isodose maps with PAGAT polymer gel dosimeter were compared to those calculated with EGSnrs for singleshot irradiations of 8 and 18 mm collimators of Gamma Knife (GK) unit in homogeneous and inhomogeneous phantoms. Materials and Methods: A custom-built, 16 cm diameter spherical Plexiglas head phantom was. Inside the phantom, there was one cubic cutout for insertion of gel phantoms, and another cutout for inserting the inhomogeneities. The phantoms were scanned with a Siemens clinical 1.5 T MRI scanner. The multiple spin-echo sequence with 32 echoes was used for the MRI scans. Results: The results of measurement and simulation in homogeneous and inhomogeneous phantoms showed that the presence of inhomogeneities in head phantom could cause spatial uncertainty higher than ±2 mm and dose uncertainty higher than 7%. Conclusion: the presence of inhomogeneities could cause dose differences which were not in accordance with accuracy in treatment with GK radiosurgery. Moreover, the findings of Monte Carlo calculation revealed that the applied simulation code (EGSnrc) was a proper tool for evaluation of 3D dose distribution in GK unit. Iran. J. Radiat. Res., 2009 7 (1): 49-56
کلیدواژه‌های انگلیسی مقاله Gamma knife, PAGAT gel dosimeter, EGSnrc, dose distribution.
نویسندگان مقاله t الهویردی پورفلاح | t allahverdi pourfallah
department of medical physics and biomedical engineering, tehran university of medical sciences, tehran, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

m اله وردی | m. allahverdi
department of medical physics and biomedical engineering, tehran university of medical sciences, tehran, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

n ریاحی عالم | n riyahi alam
department of medical physics and biomedical engineering, tehran university of medical sciences, tehran, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

محمدرضا ay | m r ay
research center for science and technology in medicine, tehran university of medical sciences, tehran, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

محمدحسین زحمتکش | m h zahmatkesh
novin medical radiation institute, tehran, iran
نشانی اینترنتی http://www.ijrr.com/browse.php?a_code=A-10-1-317&slc_lang=en&sid=en
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زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده فیزیک پزشکی
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