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International Journal of Radiation Research، جلد ۵، شماره ۲، صفحات ۵۳-۶۱

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عنوان انگلیسی Accelerated proliferation correction factors in linear-quadratic and multiple-component models
چکیده انگلیسی مقاله Background: Study in design to incorporate accelerated proliferation correction factors into linearquadratic and multiple-component models. Materials and Methods: Accelerated proliferation rate correction factor has been incorporated into the linearquadratic and the multiple component models by applying accelerated exponential cell growth to explain the tumor cell kinetics and estimates proper treatment results. Biological effectiveness and tumor control probability, in terms of BED (LQ model), BRD (MC model), TCP(LQ model) and TCP(MC model), were computed for three conventional and two accelerated hyperfractionated radiation therapy treatment schedules with using a range of accelerated proliferation rate constants to demonstrate the effect of the proliferation process. Results: The results of the study show that the accelerated proliferation rate reduces the effectiveness of a treatment schedule delivered in a prolonged period of time. Conclusion: Care should be taken in the selection of a treatment protocol for a patient of head and neck cancer with an account of the cell kinetics of the tumor.
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نویسندگان مقاله تهمینه السادات kehwar | t s kehwar
department of radiation oncology, university of pittsburgh cancer institute, pittsburgh, pa, usa


سیده فاطمه اکبر | s f akber
department of radiation oncology, case western reserve university, cleveland, ohio, usa


علی اکبر bhardwaj | a k bhardwaj
department of radiation oncology, postgraduate institute of medical education and research, chandigarh, india


v k dangwal | v k dangwal
department of radiotherapy, govt. medical college, patiala, india



نشانی اینترنتی http://www.ijrr.com/browse.php?a_code=A-10-1-234&slc_lang=en&sid=en
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کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده Radiation Biology
نوع مقاله منتشر شده تحقیق بدیع
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