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Dental Research Journal، جلد ۵، شماره ۲، صفحات ۰-۰
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عنوان انگلیسی The Effect of Locally Delivered Xanthan-Based CHLO-SITE Gel with Scaling and Root Planning in the Treatment of Chronic Periodontitis: Microbial Findings
چکیده انگلیسی مقاله Normal 0 false false false EN-US X-NONE AR-SA MicrosoftInternetExplorer4 /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Table Normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-qformat:yes; mso-style-parent:""; mso-padding-alt:0in 5.4pt 0in 5.4pt; mso-para-margin:0in; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:11.0pt; font-family:"Calibri","sans-serif"; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-fareast-font-family:"Times New Roman"; mso-fareast-theme-font:minor-fareast; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin; mso-bidi-font-family:Arial; mso-bidi-theme-font:minor-bidi;} Background: This study was designed in order to evaluate the microbiological effectiveness of a locally delivered xanthan-based CHLO-SITE gel as an adjunctive therapy to scaling and root planning in the treatment of moderate-advanced chronic periodontitis. Methods: In a randomized controlled split-mouth clinical trial, 20 patients with chronic periodontitis and pocket depth of 4-6 mm were selected. One side of the mouth served as control where scaling and root planning was performed as routine while the other side of the same mouth (experimental site) was treated by an extra injection of xanthan-based CHLO-SITE gel. Samples were taken from both sites on baseline, 1 month and 3 months post-treatment periods. Samples were exposed to nutrient material followed by colony counts. Data were then analyzed using Wilcoxon signed ranks and Friedman tests. Results: At baseline, there was no significant difference in colony counts between the control and the experimental sites (P = 0.36). However, after 1 month follow up, the mean colony count was 13850  ± 2253 and 151610 ± 11248 at experimental and control sites, respectively, with a significant difference between the two sites (P Conclusion: It seems that subgingival injection of xanthan-based CHLO-SITE gel could cause a significantly higher decrease in colony count than that of scaling and root planning therapy alone in chronic periodontitis.
کلیدواژه‌های انگلیسی مقاله Drugs, gels, periodontitis, xanthan gum.
نویسندگان مقاله | Mohmmadreza Abrishami
Professor, Department of Periodontics, School of Dentistry, Shahid Beheshti University of Medical Sciences, Tehran, Iran


| Bahram Iramloo
Associate Professor, Department of Pediatrics, School of Dentistry, Shahid Beheshti University of Medical Sciences, Tehran, Iran


| Ghassem Ansari
Assistant Professor, Department of Microbiology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran


| Gita Eslami
Assistant Professor, Department of Biostatistics, School of Paramedicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran


| Alireza Akbarzadeh Bagheban
Dental Student, School of Dentistry, Shahid Beheshti University of Medical Sciences, Tehran, Iran


| Mahdi Anaraki


نشانی اینترنتی http://drj.mui.ac.ir/index.php/drj/article/view/50
فایل مقاله اشکال در دسترسی به فایل - ./files/site1/rds_journals/171/article-171-1956208.pdf
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زبان مقاله منتشر شده en
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نوع مقاله منتشر شده Original Article(s)
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