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Middle East Journal of Digestive Diseases، جلد ۱۱، شماره ۴، صفحات ۲۲۶-۲۳۰

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عنوان انگلیسی A Rare Cause of Gastrointestinal Bleeding in a 65-Year-Old Man with History of Polycythemia Vera
چکیده انگلیسی مقاله Polycythemia vera (PV) is classified as a myeloproliferative disorder (MPD). Such patients are prone to both thrombotic and hemorrhagic events. Although gastrointestinal (GI) bleeding is not a prominent manifestation of PV, it would be life threatening and necessitating hospital admission and blood transfusion if it occurs. GI hemorrhage in these patients may be due to Aspirin usage, peptic ulcer disease (PUD), acquired VonWillbrand disease, Dieulafoy lesion (DL), Mallory Weiss tear, and esophageal and gastric varices. DL is an enlarged, thick-walled artery in the muscularis mucosa with a small submucosal defect. In this case report, we describe a 65-year-old man with history of PV presented with a massive upper GI bleeding. After a therapeutic endoscopic hemostasis failure and reoccurrence of bleeding during hospital admission, an abdominal computed tomography (CT) was ordered, which revealed an aberrant artery originated from aorta directly into the stomach. An angiographic embolization was considered for the patient, which was successfully performed. Our patient was complicated by splenic infarction due to splenic collateral arteries embolization and the overwhelming thrombotic tendency of the patient himself due to the history of PV. Fortunately, our patient’s signs and symptoms responded to supportive therapies and eventually he discharged well. KEYWORDS: Gastrointestinal bleeding, Polycythemia vera, Angioembolization, Dieulafoy lesion, Splenic infarct
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نویسندگان مقاله | Najmeh Aletaha
Tehran Medical University, gastroenterology department


| Hoda Hamid
Department of Radiology, Liver Transplantation center, Tehran University of Medical Sciences


| Niloofar Ayoobi Yazdi
Tehran Medical University, gastroenterology department


| Reza Taslimi
Tehran Medical University, gastroenterology department


| Bijan Shabazkhani
Shahid Beheshti Medical University, Internal medicine department


| Pardis Ketabi Moghadam



نشانی اینترنتی http://mejdd.org/index.php/mejdd/article/view/2093
فایل مقاله اشکال در دسترسی به فایل - ./files/site1/rds_journals/332/article-332-1989748.pdf
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زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده
نوع مقاله منتشر شده Case Report
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