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Avicenna Journal of Phytomedicine، جلد ۹، شماره ۶، صفحات ۴۹۹-۵۰۴
عنوان فارسی
چکیده فارسی مقاله
کلیدواژه‌های فارسی مقاله
عنوان انگلیسی Beneficial effects of pumpkin seed oil as a topical hair growth promoting agent in a mice model
چکیده انگلیسی مقاله Objective: Pumpkin (Cucurbita pepo L.) seed oil mainly consists of saturated and unsaturated fatty acids. Previously, it was reported that oral administration of pumpkin seed oil (PSO) improved hair growth in male pattern alopecia. This study aimed to evaluate hair promoting activity of topical PSO in an animal model. Materials and Methods: Male Swiss mice (25-30 g) were used. Dorsal hair of mice (2 x 2.5 cm) was gently removed. Groups were treated as follows: (A) Intact control (did not receive testosterone) (B) Testosterone solution only (5% w/v); (C) Testosterone (5%) + PSO (5%); (D) Testosterone (5%) + PSO (10%) (E) Testosterone (5%) + minoxidil (2%). Application of drugs (100 µl) was done for six days a week, for 3 weeks. Observational and microscopic examinations were performed and results of different groups were compared. Results: Topical application of testosterone significantly (p
کلیدواژه‌های انگلیسی مقاله Androgenic alopecia, Cucurbita pepo, pumpkin seed oil
نویسندگان مقاله | Valiollah Hajhashemi
Department of Pharmacology and Isfahan Pharmaceutical Sciences Research Center, School of Pharmacy and Pharmaceutical Sciences, Isfahan university of Medical Sciences, Isfahan, Iran.


| Parvin Rajabi
Department of Pathology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.


| Mahdieh Mardani
Department of Pharmacology and Isfahan Pharmaceutical Sciences Research Center, School of Pharmacy and Pharmaceutical Sciences, Isfahan university of Medical Sciences, Isfahan, Iran.
نشانی اینترنتی http://ajp.mums.ac.ir/article_13463.html
فایل مقاله اشکال در دسترسی به فایل - ./files/site1/rds_journals/232/article-232-2060804.pdf
کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده
نوع مقاله منتشر شده Short communication
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