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Bulletin of Emergency and Trauma، جلد ۷، شماره ۴، صفحات ۳۶۱-۳۶۵
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عنوان انگلیسی Procalcitonin and D-dimer for Predicting 28-Day-Mortality Rate and Sepsis Severity based on SOFA Score; A Cross-sectional Study
چکیده انگلیسی مقاله Objective: To determine the possible relationship of procalcitonin (PCT) and D-dimer with the 28-day-mortality rate and severity of sepsis based on sequential organ failure assessment (SOFA) score. Methods: In this cross-sectional study, patients were enrolled based on their signs and symptoms of sepsis confirmed by essential laboratory studies. Demographic data, Glasgow coma scale and vital signs, serum PCT and D-dimer levels, creatinine, bilirubin level, arterial blood gas analysis and platelet count were recorded. Disease severity index was assessed based on SOFA score. Patients’ 28-day-mortality rate and hospital length of stay were compared with the study variables. Results: Sixty-four patients with the mean age of 78.3±11.6 were included of whom 34 cases (53.1%) were male. The 28-day-mortality rate was 17%. The analysis showed that only patients’ age (p=0.01) and platelet count (p=0.02) had a statistically significant association with the mortality rate. SOFA score had no statistically significant correlation with PCT or D-dimer; and these two markers didn’t have any significant correlation in terms of predicting mortality due to the sepsis. Conclusion: In our study, PCT and D-dimer failed to show any significant correlation with 28-day-mortality rate of sepsis.
کلیدواژه‌های انگلیسی مقاله Fibrin fragment D,Mortality,Procalcitonin,Prognosis,Sepsis
نویسندگان مقاله Zeinab Naderpour |
Department of Internal Medicine, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran

Mehdi Momeni |
Prehosptal and Hospital Research Center, Tehran University of Medical Sciences, Tehran, Iran. Department of Emergency Medicine, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran.

Elnaz Vahidi |
Prehosptal and Hospital Research Center, Tehran University of Medical Sciences, Tehran, Iran. Department of Emergency Medicine, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran.

Javad Safavi |
Department of Emergency Medicine, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran.

Morteza Saeedi |
Prehosptal and Hospital Research Center, Tehran University of Medical Sciences, Tehran, Iran. Department of Emergency Medicine, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran.

نشانی اینترنتی http://beat.sums.ac.ir/article_45809_3b1f44f28b8b043135ca4c7eb23d8ffb.pdf
فایل مقاله اشکال در دسترسی به فایل - ./files/site1/rds_journals/271/article-271-2060865.pdf
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