این سایت در حال حاضر پشتیبانی نمی شود و امکان دارد داده های نشریات بروز نباشند
Bulletin of Emergency and Trauma، جلد ۳، شماره Issue ۳، صفحات ۹۷-۱۰۳
عنوان فارسی
چکیده فارسی مقاله
کلیدواژه‌های فارسی مقاله
عنوان انگلیسی Administration of Intravenous Infliximab for Prevention of Peritoneal Adhesions Formation in Rats
چکیده انگلیسی مقاله Objectives: To investigate the effects of intravenous infliximab in preventing the formation of peritoneal adhesions in an animal model of rat.Methods: This was an experimental study being performed in animal laboratory of Shiraz University of Medical Sciences during 2012. Sixty albino rats were randomly assigned in to three groups by Random Design Method. The first group received single infliximab injection (n=20), the second one received double infliximab injection (n=20) and the third received nothing (n=20), after receiving intra-peritoneal injection of talc for induction of peritoneal adhesions. All the animals were sacrificed after 6 weeks and the peritoneal adhesions were evaluated according to Nair classification.Results: We observed that the mean adhesion grade was lower in those who received double dose of infliximib when compared to single dose and controls. However the difference did not reach a significant value (p=0.178). The grade of peritoneal adhesion was also comparable between the three study groups (p=0.103). The mean number of 1st WBC count was also comparable between three study groups (p=0.382). We observed that 2nd WBC count was also comparable between two study groups (p=0.317).Conclusion: Administration of intravenous infliximab after intraabdominal surgicalprocedures would not prevent the formation of peritoneal adhesions in animal model of albino rat.
کلیدواژه‌های انگلیسی مقاله
نویسندگان مقاله Saman Nikeghbalian |


Homeira Vafaei |


Farid Moradian |


Kourosh Kazemi |


Nader Tanideh |


Leila Shayan |
MSc, Trauma Research Center, Shiraz University of Medical Sciences, Shiraz, Iran

Zahra Nikeghbalian |


نشانی اینترنتی http://beat.sums.ac.ir/article_44296_a61a161872a52b97a1dc06d900ffe261.pdf
فایل مقاله اشکال در دسترسی به فایل - ./files/site1/rds_journals/271/article-271-2061056.pdf
کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده
نوع مقاله منتشر شده
برگشت به: صفحه اول پایگاه   |   نسخه مرتبط   |   نشریه مرتبط   |   فهرست نشریات