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International Journal of Engineering، جلد ۳۱، شماره ۸، صفحات ۱۳۰۸-۱۳۱۷
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عنوان انگلیسی Inhibitory Effects of Swietenia Mahagoni Seeds Extract on Α-Glucosidase and Α-amylase
چکیده انگلیسی مقاله This study analyzed the inhibition activity of Swietenia mahagoni seeds extract on α-glucosidase and α-amylase enzymes inhibition assays. Swietenia mahagoni seeds were extracted by using Supercritical Carbon Dioxide (SC-CO2) extraction at pressures of 20- 30 MPa and temperatures of 40- 60°C. The oil yields obtained were analyzed with α- glucosidase and α- amylase enzymes inhibition assays. All data obtained were expressed as mean ± standard deviation for triplicate experiments. One way analysis was used for statistical significance by using Statistica software version 7.0 (StartSoft, EUA) and IC50 (extract concentration causing 50% enzyme inhibitory) was determined by using GraphPad Prism 6.0 software. Swietenia mahagoni seeds extract have a strong inhibition of α-glucosidase enzyme activity (98.4% ± 0.2) but a moderate inhibition of α- amylase enzyme activity (34.9% ± 1.2). These findings implied that Swietenia mahagoni seeds extract could be an effective natural antidiabetic agent.
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نویسندگان مقاله Nor Asyiqin Bakeri |
Department of Bioprocess and Polymer Engineering, Universiti Teknologi Malaysia

Mohd Amzar Mohamed Zahari |
Department of Bioprocess and Polymer Engineering, Universiti Teknologi Malaysia

Firdaus Kamarulzaman |
Natural Product Division, Forest Research Institute Malaysia (FRIM)

Nohaniza Yusof |
Advanced Membrane Technology Research Centre (AMT, Universiti Teknologi Malaysia

Nik Musaadah Mustafa |
Natural Product Division, Forest Research Institute Malaysia (FRIM)

Liza Md Salleh |
Department of Bioprocess and Polymer Engineering, Universiti Teknologi Malaysia

Nur Salsabila Md Norodin |
BIOPROCESS AND POLYMER ENGINEERING, Universiti Teknologi Malaysia

نشانی اینترنتی http://www.ije.ir/article_73249_5b75c9ebc188c87fa8900513ae08929b.pdf
فایل مقاله اشکال در دسترسی به فایل - ./files/site1/rds_journals/409/article-409-2061785.pdf
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زبان مقاله منتشر شده en
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