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JCR 2016
جستجوی مقالات
دوشنبه 24 آذر 1404
Journal of Medical Signals and Sensors
، جلد ۱۰، شماره ۱، صفحات ۴۲-۴۷
عنوان فارسی
چکیده فارسی مقاله
کلیدواژههای فارسی مقاله
عنوان انگلیسی
The Measurement of Thyroid Absorbed dose by Gafchromic™ EBT2 Film and Changes in Thyroid Hormone Levels Following Radiotherapy in Patients with Breast Cancer
چکیده انگلیسی مقاله
Background: Radiotherapy is a main method for the treatment of breast cancer. This study aimed to measure the absorbed dose of thyroid gland using Gafchromic EBT2 film during breast cancer radiotherapy. In addition, the relationship between the absorbed dose and thyroid hormone levels was evaluated. Methods: Forty-six breast cancer patients, with the age ranged between 25 and 35 years, undergoing external radiotherapy were studied. The patients were treated with 6 and 18 MV X-ray beams, and the absorbed thyroid dose was measured by EBT2 film. Thyroid hormone levels, thyroid-stimulating hormone (TSH), triiodothyronine (T3), and thyroxin (T4), were measured before and after the radiotherapy. Pearson's, Spearman's, and Chi-square tests were performed to evaluate the correlation between the thyroid dose and hormone levels. Results: The mean thyroid dose was 26 ± 9.45 cGy with the range of 7.85-48.35 cGy. There were not any significant differences at thyroid hormone levels between preradiotherapy and postradiotherapy (P > 0.05). There was a significant relationship between increased thyroid absorbed dose and changes in TSH and T4 levels (P < 0.05), but it was not significant in T3 level (P = 0.1). Conclusion: Regarding the results, the thyroid absorbed dose can have an effect on its function. Therefore, the thyroid gland should be considered as an organ at risk in breast cancer radiotherapy.
کلیدواژههای انگلیسی مقاله
Breast cancer, Gafchromic film, radiotherapy, thyroid gland
نویسندگان مقاله
| Leyla Ansari
| Neda Nasiri
| Fahimeh Aminolroayaei
| Karim Ghazikhanlou Sani
| Masoumeh Dorri-Giv
| Razzagh Abedi-Firouzjah
| Dariush Sardari
نشانی اینترنتی
http://jmss.mui.ac.ir/index.php/jmss/article/view/519
فایل مقاله
اشکال در دسترسی به فایل - ./files/site1/rds_journals/217/article-217-2273139.pdf
کد مقاله (doi)
زبان مقاله منتشر شده
en
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نوع مقاله منتشر شده
Original Articles
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