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Middle East Journal of Cancer، جلد ۱۱، شماره ۲، صفحات ۱۶۸-۱۷۳
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عنوان انگلیسی Treatment-related Complications in Childhood Acute Lymphoblastic Leukemia: Results of Medical Research Council UKALL X
چکیده انگلیسی مقاله Background: Acute lymphoblastic leukemia (ALL) is a heterogeneous group of lymphoid neoplasms resulting from the proliferation of malignant lymphoid cells. The aim of this study was to evaluate treatment-related complications in children with ALL receiving the Medical Research Council (MRC) UKALL X protocol. Methods: In this retrospective cross-sectional study, children with ALL receiving the MRC UKALL X protocol from 2008 to 2015 in Bahrami University Hospital, Iran, were enrolled. The clinical and morphological features were analysed and treatment-related complications were assessed. Results: Out of 67 children with ALL receiving the MRC UKALL X protocol, 44 (65.6 %) were boys and 23 (34.4%) were girls. Seven patients (10.7%) relapsed in the three years of diagnosis, and 50 children (74.6%) had an overall survival of three years. Average age in three-year-survival group and mortality group was 6.92 (SD: 3.96) and 6.35 (SD: 7.47), respectively (P= 0.38). Conclusion: Overall survival and relapse rates in this study confirm that this protocol is an appropriate treatment strategy.
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نویسندگان مقاله Ehsan Shahverdi |
Department of Cardiology, Angiology and Sleep Medicine, Bonifatius Hospital Lingen, Lingen, Germany

Pedram Karami |
Department of Otorhinolaryngology-Head and Neck Surgery, Rasoul Akram Hospital, Iran University of Medical Sciences, Tehran, Iran

Farzaneh Tavakoli |
Hematopoietic Stem Cell Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran

Massoumeh Maki |
Department of Nursing and Midwifery, Falavarjan Branch, Islamic Azad University, Isfahan, Iran

Meysam Moazzami |
Department of Pediatrics, Firouzgar Hospital, Iran University of Medical Sciences, Tehran, Iran

Fatemeh Feizi |
Department of Laboratory Hematology and Blood Bank, School of Allied Medical Sciences, Shahid Beheshi University of Medical Science, Tehran, Iran

Peyman Salamati |
Department of Pediatrics, Tehran University of Medical Sciences, Tehran, Iran

Alireza Lotfipour |
Department of Pediatrics, Tehran University of Medical Sciences, Tehran, Iran

Mohammad Ali Ehsani |
Department of Pediatrics, Tehran University of Medical Sciences, Tehran, Iran

نشانی اینترنتی http://mejc.sums.ac.ir/article_46416_b9411c18676cbc9066f2d4aaf8d9d049.pdf
فایل مقاله اشکال در دسترسی به فایل - ./files/site1/rds_journals/181/article-181-2348892.pdf
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