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Middle East Journal of Cancer، جلد ۱۱، شماره ۲، صفحات ۱۹۸-۲۰۲
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عنوان انگلیسی Serum and Urine Levels of Vascular Endothelial Growth Factor as Prognostic Markers in Patients with Bladder Cancer
چکیده انگلیسی مقاله Background: Bladder cancer is the second most common urinary cancer after prostate cancer. Recent studies have shown higher serum and urinary vascular endothelial growth factor (VEGF) in increased angiogenesis. In this study, the mean serum and urine level of VEGF was assessed in patients with bladder cancer. Methods: In this case-control study, 46 patients with bladder cancer referred to Imam-Khomeini Hospital in Tehran, Iran and 38 subjects as control, were enrolled and the mean serum and urine level of VEGF was assessed and compared between the groups. Results: The mean serum level of VEGF was 478.7, 518.4, and 648.1 in control, low-grade, and high-grade groups, respectively, with no significant difference (P=0.175). The mean urine level of VEGF was 414.2, 968.3, and 848.4 in control, low-grade, and high-grade groups, respectively, with significant difference (P=0.010). Conclusion: The mean urine level of VEGF in patients with bladder cancer is higher than healthy subjects.
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نویسندگان مقاله Mohsen Ayati |
Uro-Oncology Research Center, Tehran University of Medical Sciences, Tehran, Iran

Hossein Ghorani |
Uro-Oncology Research Center, Tehran University of Medical Sciences, Tehran, Iran

Erfan Amini |
Uro-Oncology Research Center, Tehran University of Medical Sciences, Tehran, Iran

Mohammad Reza Nowroozi |
Uro-Oncology Research Center, Tehran University of Medical Sciences, Tehran, Iran

Hassan Jamshidian |
Uro-Oncology Research Center, Tehran University of Medical Sciences, Tehran, Iran

Solmaz Ohadian Moghadam |
Uro-Oncology Research Center, Tehran University of Medical Sciences, Tehran, Iran

نشانی اینترنتی http://mejc.sums.ac.ir/article_46424_2aeedfc589ebfb21a5e0aeea84b8f1d4.pdf
فایل مقاله اشکال در دسترسی به فایل - ./files/site1/rds_journals/181/article-181-2348896.pdf
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