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Iranian Journal of Microbiology، جلد ۱۲، شماره ۲، صفحات ۱۶۴-۱۶۹
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عنوان انگلیسی Survey of WU and KI polyomaviruses, coronaviruses, respiratory syncytial virus and parechovirus in children under 5 years of age in Tehran, Iran
چکیده انگلیسی مقاله Background and Objectives: Severe acute respiratory infections (SARI) remain an important cause for childhood morbidity worldwide. We designed a research with the objective of finding the frequency of respiratory viruses, particularly WU and KI polyomaviruses (WUPyV & KIPyV), human coronaviruses (HCoVs), human respiratory syncytial virus (HRSV) and human parechovirus (HPeV) in hospitalized children who were influenza negative. Materials and Methods: Throat swabs were collected from children younger than 5 years who have been hospitalized for SARI and screened for WUPyV, KIPyV, HCoVs, HRSV and HPeV using Real time PCR. Results: A viral pathogen was identified in 23 (11.16%) of 206 hospitalized children with SARI. The rate of virus detection was considerably greater in infants < 12 months (78.2%) than in older children (21.8%). The most frequently detected viruses were HCoVs with 7.76% of positive cases followed by KIPyV (2%) and WUPyV (1.5%). No HPeV and HRSV were detected in this study. Conclusion: This research shown respiratory viruses as causes of childhood acute respiratory infections, while as most of mentioned viruses usually causes mild respiratory diseases, their frequency might be higher in outpatient children. Meanwhile as HRSV is really sensitive to inactivation due to environmental situations and its genome maybe degraded, then for future studies, we need to use fresh samples for HRSV detection. These findings addressed a need for more studies on viral respiratory tract infections to help public health.
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نویسندگان مقاله | Fahimeh Sadat Aghamirmohammadali
Department of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran


| Kaveh Sadeghi
Department of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran


| Nazanin Zahra Shafiei-Jandaghi
Department of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran


| Zahra Khoban
Department of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran


| Talat Mokhtari-Azad
Department of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran


| Jila Yavarian
Department of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
نشانی اینترنتی http://ijm.tums.ac.ir/index.php/ijm/article/view/2448
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