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Acta Medica Iranica، جلد ۵۷، شماره ۹، صفحات ۵۶۰-۵۶۴
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عنوان انگلیسی Prevalence and serotype determination of Streptococcus. agalactiae isolated from non-pregnant women in Tehran, Iran
چکیده انگلیسی مقاله Consequence of Streptococcus. agalactiae, Group B Streptococcus (GBS) relating infant’s diseases are well documented. Although many women carry this bacterium in their vagina, they may transfer to their infant during delivery and may results in different neonatal invasive diseases. The aim of this study was to determine the prevalence of GBS and serotyping the isolated species among un-selective non-pregnant women attended two gynecology clinics in Tehran. In this cross-sectional study, a total of 560 vaginal samples collected from non-pregnant women. Following inoculation of specimen on BA, the standard technology was applied for final identification of GBS. Detected GBS species were further confirmed using specific PCR directed on dlts gene. Capsular serotyping was done by using the multiplex PCR method. The chi-square method was used for statistical analysis. Fifty (8.9%) out of 560 non-pregnant women were carries of GBS. The most common types were III (36%), followed by type II (32%), Ia (26%) and Ib (6%) respectively. Results represent that the prevalence rate of GBS in non-pregnant women was reliable and similar to what obtained from pregnant women. In addition, the serotype III was found the most dominant types as well as other investigations in Tehran area. Therefore, vaccine designation based on type III is recommended. Keywords: Group B Streptococcus, multiplex PCR, non-pregnant women, capsular serotyping
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نویسندگان مقاله | Leila Goudarzi
Department of microbiology, School of Medicine, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.


| Mohammad bagher Khalili
2- Department of Microbiology, Faculty of Medicine, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.


| Mahmood Vakili
3- Department of Public Medicine, Faculty of Medicine, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.


| maryam sadeh
Department of Laboratory Sciences, School of Paramedicine, Shahid Sadoughi University of Medical Science, Yazd, Iran.
نشانی اینترنتی http://acta.tums.ac.ir/index.php/acta/article/view/7813
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