این سایت در حال حاضر پشتیبانی نمی شود و امکان دارد داده های نشریات بروز نباشند
International Journal of Organ Transplantation Medicine، جلد ۱۱، شماره ۲، صفحات ۰-۰
عنوان فارسی
چکیده فارسی مقاله
کلیدواژه‌های فارسی مقاله
عنوان انگلیسی De-novo Upper Gastrointestinal Tract Cancer after Liver Transplantation: A Demographic Report
چکیده انگلیسی مقاله Background: Immunosuppression is essential after liver transplantation (LT). It, however, increases the risk for cancer. Objective: To evaluate the prevalence and outcome of upper gastrointestinal (GI) tract cancer in LT patients and assess the perioperative risk of surgery for the upper GI malignancies post-LT. Methods: 2855 patients underwent LT at our clinic from 1988 to 2018. 20 patients developed upper GI cancer. Data were retrospectively extracted from our database. Analysis included patients’ specific data, tumor histopathology and stage, the treatment given and survival. Results: 23 patients developed upper GI malignancies (2 gastric and 18 esophageal cancers; 3 excluded), translating to a incidence of 26.4 per 100,000 population per year. All patients were male. 80% showed alcohol-induced cirrhosis before LT. Most of the tumors were diagnosed at a stage ≥III. 70% underwent surgery and 78.6% developed postoperative complications. One-year-survival was 50%. Total survival rate was 28.6% with a median follow-up of 10 months (range: 0–184). Conclusion: Upper GI malignancies are more common after LT compared to the general population. Men after LT, due to alcohol-induced liver cirrhosis, are at a higher risk. Upper GI surgery after LT can be safe, but the severe risk for complications and a poor survival require strict indications.
کلیدواژه‌های انگلیسی مقاله
نویسندگان مقاله | E M Dobrindt
Department of Surgery, Charité – Universitätsmedizin Berlin, Berlin, Germany


| M Biebl
Department of Surgery, Charité – Universitätsmedizin Berlin, Berlin, Germany


| S Rademacher
Department of Visceral, Transplant, Thoracic and Vascular Surgery, Universitätsklinikum Leipzig, Leipzig, Germany


| C Denecke
Department of Surgery, Charité – Universitätsmedizin Berlin, Berlin, Germany


| A Andreou
Department of Surgery, Charité – Universitätsmedizin Berlin, Berlin, Germany


| J Raakow
Department of Surgery, Charité – Universitätsmedizin Berlin, Berlin, Germany


| D Kröll
Department of Surgery, Charité – Universitätsmedizin Berlin, Berlin, Germany


| R Öllinger
Department of Surgery, Charité – Universitätsmedizin Berlin, Berlin, Germany


| J Pratschke
Department of Surgery, Charité – Universitätsmedizin Berlin, Berlin, Germany


| S S Chopra
Department of Surgery, Charité – Universitätsmedizin Berlin, Berlin, Germany
نشانی اینترنتی http://www.ijotm.com/ojs/index.php/IJOTM/article/view/698
فایل مقاله اشکال در دسترسی به فایل - ./files/site1/rds_journals/221/article-221-2386782.pdf
کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده
نوع مقاله منتشر شده Original Articles
برگشت به: صفحه اول پایگاه   |   نسخه مرتبط   |   نشریه مرتبط   |   فهرست نشریات