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Journal of Basic Research in Medical Sciences، جلد ۷، شماره ۴، صفحات ۲۰-۳۰
عنوان فارسی
چکیده فارسی مقاله
کلیدواژه‌های فارسی مقاله
عنوان انگلیسی The effect of twelve weeks of combined training with and without canagliflozin consumption on fetuin A and fetuin B in type 2 diabetic men
چکیده انگلیسی مقاله Introduction: Cardiovascular disease, diabetes, and fatty liver are now considered the major causes of mortality in developing countries. The present study investigates the effect of twelve weeks of combined training with and without canagliflozin consumption on fetuin-A and fetuin B in type 2 diabetic men. Materials and Methods: Forty- four men (25-40 years ) who had type two diabitiac were recruited for this study. This is a double-blind study conducted in four groups. For this purpose, diabetic men were divided into four groups of 11 individuals, including control-diabetes, diabetes-medication, diabetes-training, and diabetes-training-supplementation. Every day, 200 mg of canagliflozin and placebo were given to medication-consuming and placebo groups. Blood samples were taken before and 48 hours after the last training session and used for analysis. Results: Two-way ANOVA results showed a significant difference between groups (P< 0.001) for fetuin A-amounts. Bonferroni test results also showed a significant difference between control and training (P = 0.030), control and medication-training (P< 0.001), medication-training, and medication (P< 0.001) and medication-training and training (P= 0.001) groups. The two-way analysis of variance showed significant differences between groups (P = 0.023) in terms of fetuin B amounts. The post hoc test results showed a significant difference between control and training groups (P = 0.009) and control with training-medication groups (P = 0.007). Conclusion: According to our results, the administration of a combination program, alongside the use of canagliflozin, on individuals who have type 2 diabetes may have the most significant effect on reducing these hepatokines in people with diabetes.
کلیدواژه‌های انگلیسی مقاله Combined Exercise, Hepatokine, Type 2 Diabetes, Canagliflozin
نویسندگان مقاله | Ali Samadi
Department of Exercise Physiology, Ayatollah Amoli Branch, Islamic Azad University, Amol, Iran


| Asieh Abbassi Daloii
Department of Exercise Physiology, Ayatollah Amoli Branch, Islamic Azad University, Amol, Iran


| Alireza Barari
Department of Exercise Physiology, Ayatollah Amoli Branch, Islamic Azad University, Amol, Iran


| Ayoub Saeidi
Department of Exercise Physiology, Damghan Branch, Islamic Azad University, Damghan, Iran
نشانی اینترنتی http://jbrms.medilam.ac.ir/browse.php?a_code=A-10-361-2&slc_lang=en&sid=1
فایل مقاله اشکال در دسترسی به فایل - ./files/site1/rds_journals/358/article-358-2473774.pdf
کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده Public health
نوع مقاله منتشر شده پژوهشی
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