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Iranian Journal of Otorhinolaryngology، جلد ۳۳، شماره ۵، صفحات ۳۲۷-۳۳۲
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عنوان انگلیسی Burkholderia Cepacia Causes Frontal Mucopyocele with Anterior Cranial Fossa Extension: A Novel Case Report
چکیده انگلیسی مقاله Introduction: Burkholderia cepacia complex (Bcc) is a group of gram-negative bacilli that have rarely been isolated in the ear, nose and throat region in immunocompetent patients. Bcc show resistance to most available antibacterial drugs. Case Report: We present the case of an immunocompetent 31-year-old male reporting a pulsating headache with right supraorbital swelling associated with exophthalmos. A brain CT scan showed an expansive giant cystic lesion occupying the right frontal sinus, extending to the anterior cranial fossa. Management and outcome: drainage with the resecting of the floor of the frontal sinus from the orbital plate of the ethmoid bone to the nasal septum (Draf IIb) was performed with wide marsupialization of the mucopyocele. Polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) analysis was used to identify the isolate. MRI 1 and 12 months after surgery showed complete lesion removal. The patient was followed for 12 months with complete recovery of symptoms. Conclusion: Paranasal sinuses disease with cranial expansion and orbital complications constitutes an emergency. For the first time in the literature, Bcc was isolated in the frontal sinus, extending into the anterior cranial fossa, in an immunocompetent patient. An endoscopic surgical approach with microbiological identification and management by appropriate antibacterial drug treatment seems to be the key to success.
کلیدواژه‌های انگلیسی مقاله Burkholderia cepacia complex, mucocele, Frontal sinus, Surgical Endoscopy, Culture Media
نویسندگان مقاله | Athanasios Saratziotis
Department of Otolaryngology, General University Hospital of Larisa, Greece.


| Claudia Zanotti
Department of Neurosciences, Otolaryngology Section, University of Padua, Italy.


| Maria Baldovin
Department of Neurosciences, Otolaryngology Section, University of Padua, Italy.


| Vlatko Prosenikliev
Department of Otolaryngology, General Hospital San Dona di Piave, Venice, Italy.


| Enzo Emanuelli
Department of Neurosciences, Otolaryngology Section, University of Padua, Italy.
نشانی اینترنتی https://ijorl.mums.ac.ir/article_18636.html
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