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Physiology and Pharmacology، جلد ۲۵، شماره ۲، صفحات ۱۰۲-۱۰۷
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عنوان انگلیسی Complements C3 and C4 in serum and stimulatedsaliva of patients suffer oral erosive lichen planus
چکیده انگلیسی مقاله Introduction: The objective of this study was to compare the level of complements C3 and C4 in serum, and stimulated saliva between oral lichen planus (OLP) and healthy individuals. Methods: A case-control study was performed on 31 healthy and 31 who suffer the erosive type of OLP. Serum and saliva level of C3 and C4 were measured by immunoturbidimetry method. Results: C3 and C4 were expressed at a lower level in serum and saliva of OLP patients compared to control groups. Serum C3 and C4 levels did not correlate with their saliva levels. The receiver operating characteristic analysis showed significantly diagnostic abilities for serum and saliva C3 and C4 to discrimination of OLP patients from controls (cutoff [mg/dl] for C3 were 83 in serum and 3.45 in saliva and for C4 were 9.5 in serum and 0.9 in saliva). Conclusion: Serum and salivary levels of total C3 and C4 were lower in patients with OLP than in healthy controls. Therefore, they may able to discriminate OLP from healthy.
کلیدواژه‌های انگلیسی مقاله Complement C3, Complement C4, Oral lichen planus, Saliva, Serum.
نویسندگان مقاله | Mohammad-Hossein Mirzaii-Dizgah
Student Research Committee, School of Dentistry, Aja University of Medical Sciences, Tehran, Iran


| Bita Rohani
Department of Oral Medicine, School of Dentistry, Aja University of Medical Sciences, Tehran, Iran


| Iraj Mirzaii-Dizgah
Department of Physiology, School of Medicine, Aja University of Medical Sciences, Tehran, Iran
نشانی اینترنتی http://ppj.phypha.ir/browse.php?a_code=A-10-1407-1&slc_lang=en&sid=1
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زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده Others
نوع مقاله منتشر شده Experimental research article
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