این سایت در حال حاضر پشتیبانی نمی شود و امکان دارد داده های نشریات بروز نباشند
International Journal of Radiation Research، جلد ۲۰، شماره ۱، صفحات ۱۰۹-۱۱۴
عنوان فارسی
چکیده فارسی مقاله
کلیدواژه‌های فارسی مقاله
عنوان انگلیسی Observation of the effectiveness and safety of the combination of chemotherapy and radiotherapy after the radical resection of progressive gastric cancer
چکیده انگلیسی مقاله Background: To analyze the effectiveness and safety of combination of 3-dimensional conformal radiotherapy (3D-CRT) and S-LOX chemotherapy after the radical resection of localized progressive gastric cancer, so as to provide the reference for clinical treatment. Materials and Methods: We enrolled 82 localized progressive gastric cancer patients undergoing the radical resection of gastric cancer, and divided them using the random digit table into two groups: 39 in the chemotherapy group received the S-LOX chemotherapy after operation, and 43 in the combination group received the 3D-CRT in combination with S-LOX chemotherapy. After treatment, we evaluated the clinical efficacy, adverse reaction, survival rate and recurrence rate of patients in two groups. Results: After 6 cycles of treatment, we found no statistical significance in difference of the objective remission rate of patients in two groups (P > 0.05), while the patients in the combination group excelled in the clinical control rate (P < 0.05). In the combination group, 2-year survival rate and survival time of patients were all higher and longer than those in the chemotherapy group (all P < 0.05), with a lower recurrence rate (P < 0.05). Furthermore, comparison of the incidence of adverse reactions of patients between two groups showed no significant difference (P > 0.05). Conclusion: After the radical resection of the localized progressive gastric cancer,           3D-CRT in combination with S-LOX chemotherapy improves the clinical control and survival of patients, while reduces the postoperative recurrence, but with no aggravation in side- or toxic-effect, thus worthy of being promoted in clinical practice.  
کلیدواژه‌های انگلیسی مقاله Progressive gastric cancer, radical resection, chemotherapy, 3D-CRT, prognosis.
نویسندگان مقاله | R. Zhang
Department of Radiotherapy, Linyi Central Hospital, Linyi, Shandong276400, China


| R. Zhang
Department of Radiotherapy, Linyi Central Hospital, Linyi, Shandong276400, China


| S. Cao
Department of Radiotherapy Room, Linyi Central Hospital, Linyi, Shandong276400, China


| S. Cui
Department of General Surgery II Ward, Linyi Central Hospital, Linyi, Shandong276400, China


| C. Liu
Department of General Surgery II Ward, Linyi Central Hospital, Linyi, Shandong276400, China


| J. Wang
Department of General Surgery II Ward, Linyi Central Hospital, Linyi, Shandong276400, China


| X. Cheng
Department of General Surgery II Ward, Linyi Central Hospital, Linyi, Shandong276400, China
نشانی اینترنتی http://ijrr.com/browse.php?a_code=A-10-2188-69&slc_lang=en&sid=1
فایل مقاله فایلی برای مقاله ذخیره نشده است
کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده Radiobiology
نوع مقاله منتشر شده تحقیق بدیع
برگشت به: صفحه اول پایگاه   |   نسخه مرتبط   |   نشریه مرتبط   |   فهرست نشریات