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International Journal of Radiation Research، جلد ۲۰، شماره ۱، صفحات ۲۴۱-۲۴۴
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عنوان انگلیسی Target dose accuracy of single-isocenter stereotactic body radiation therapy for multiple lung lesions
چکیده انگلیسی مقاله Background: To investigate the maximum distance from lesions to the single-isocenter that can ensure the accuracy of dose delivery for single-isocenter/two-lesions intensity modulated radiotherapy (IMRT) lung stereotactic body radiation therapy (SBRT). Materials and Methods: We employed a lung phantom made of acrylic material. Sixteen gross tumor volumes (GTVs) of the same shape and size were delineated on the CT images. The single-isocenter was placed on the center of the first GTV (GTV1). Six GTV centers were located at left and were 2-7 cm away from the single-isocenter. Nine GTV centers were in the 45° direction and were 2-10 cm away from the single-isocenter. Plans were created for the first planning target volume (PTV1) and other fifteen PTVs separately with the same isocenter. Compass was used to verify the treatment plans. γ analysis was carried out with criteria of 2% / 2 mm. The passing rate shall over than 90%. If the passing rate of γ analysis was lower than 90%, two-isocenter plan was created and carried out γ analysis as well. Results: According to the γ analysis, when the distance from lesions to the single-isocenter was more than 6cm, both in the horizontal or 45° direction, the passing rate was lower than 90%. Based on γ analysis, two-isocenter plans were created. After verification, the passing rate was higher than 90%. Conclusions: The maximum distance of using single-isocenter to treat multiple lung lesions is 5 cm. The result provides a reference for our center and other centers when using this technique to treat multiple lung lesions.
کلیدواژه‌های انگلیسی مقاله Multiple lung lesions, single-isocenter, SBRT, dose accuracy.
نویسندگان مقاله | Y. Shao
Institute of Modern Physics, Fudan University, Shanghai, 200433 China


| H. Chen
Institute of Modern Physics, Fudan University, Shanghai, 200433 China


| H. Wang
Institute of Modern Physics, Fudan University, Shanghai, 200433 China


| Y. Cheng
Department of Radiation Oncology, Shanghai Chest Hospital, Shanghai Jiao Tong University, Shanghai, 20030, China


| Z. Zhu
Department of Radiation Oncology, Shanghai Chest Hospital, Shanghai Jiao Tong University, Shanghai, 20030, China


| W. Zhuo
Institute of Radiation Medicine, Fudan University, Shanghai, 20032, China


| Q. Kong
Institute of Modern Physics, Fudan University, Shanghai, 200433 China


| H.J. Albazoni
Department Department of Environmental Sciences, Faculty of Science, University of Kufa, Najaf, Iraq
نشانی اینترنتی http://ijrr.com/browse.php?a_code=A-10-2188-89&slc_lang=other&sid=1
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کد مقاله (doi)
زبان مقاله منتشر شده other
موضوعات مقاله منتشر شده Radiobiology
نوع مقاله منتشر شده یادداشت فنی
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