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International Journal of Radiation Research، جلد ۱۹، شماره ۳، صفحات ۷۴۹-۷۵۳
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چکیده فارسی مقاله
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عنوان انگلیسی Successful treatment of a patient with an EGFR-mutated pulmonary adenocarcinoma and a history of uremia with erlotinib after gefitinib-induced kidney dysfunction: a case report
چکیده انگلیسی مقاله A 48-year-old male patient with a history of uremia was diagnosed with pulmonary adenocarcinoma based on a computed tomography (CT) scan and biopsy. In addition, an epidermal growth factor receptor (EGFR) exon 19 deletion was identified by gene detection. Surgical treatment was not acceptable because of his poor physical condition, so he was treated with gefitinib. Kidney function deteriorated and the serum urea nitrogen and creatinine levels were increased. Two weeks after discontinuing treatment with gefitinib, kidney function gradually returned to normal and was treated with erlotinib. This is an unusual case involving a patient with EGFR-mutated pulmonary adenocarcinoma and a history of uremia who was successfully treated with erlotinib after gefitinib-induced kidney dysfunction.
کلیدواژه‌های انگلیسی مقاله Epidermal growth factor receptor, pulmonary adenocarcinoma, Erlotinib, gefitinib, kidney function.
نویسندگان مقاله | L. Zhou
Respiratory ward 2, PCCM, Affiliated Hospital of Zunyi Medical University, Zunyi City, 563003, China


| Z. Chen
Respiratory ward 2, PCCM, Affiliated Hospital of Zunyi Medical University, Zunyi City, 563003, China
نشانی اینترنتی http://ijrr.com/browse.php?a_code=A-10-2188-50&slc_lang=en&sid=1
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کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده Radiobiology
نوع مقاله منتشر شده مطالعه موردی
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