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Acta Medica Iranica، جلد ۵۸، شماره ۶، صفحات ۲۷۵-۲۷۸
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عنوان انگلیسی Study on Anticardiolipin Antibodies in Women With Recurrent Abortion in Duhok Province, Kurdistan Region, Iraq
چکیده انگلیسی مقاله Recurrent abortion is a worldwide issue. Anticardiolipin antibodies (ACA) are found to be among the most important factors related to recurrent spontaneous early pregnancy loss. This study aimed to investigate the prevalence of anticardiolipin IgM and IgG antibodies in women with recurrent abortion in Kurdistan Region of Iraq. The present study was conducted in Duhok and Zakho cities for the period from April 2014 to May 2019. A total of 1230 women aged between 18 to 46-year-old were included in this study. ELISA was used for the detection of anticardiolipin antibodies. Among the studied subjects, the prevalence of anticardiolipin antibodies was 74 (6.02%) for ACA IgM and 56 (4.6%) for ACA IgG. It was also observed that 16 (1.3%) subjects were positive for both ACA IgM and IgG antibodies. Additionally, the highest anticardiolipin antibody positivity rates were recorded in patients older than 30-year-old (P< 0.01). The IgM ACA positivity was higher in Zakho city 45 (7.2%) when compared to Duhok city 29 (4.6%) (P< 0.04). In conclusion, anticardiolipin antibodies can have a positive association among women with recurrent abortion. Therefore, it is suggested that women with recurrent abortion should be screened for anticardiolipin antibodies; this could increase fetal survival by initiating early anticoagulant therapy when other causes of abortion are excluded.    
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نویسندگان مقاله | Ibrahim Naqid
Department of Biomedical Sciences, College of Medicine, University of Zakho, Zakho Kurdistan Region, Iraq


| Shivan Yousif
Department of Biomedical Sciences, College of Medicine, University of Zakho, Zakho Kurdistan Region, Iraq


| Amer Balatay
Department of Pharmacology and Clinical Pharmacy, College of Pharmacy, University of Duhok, Kurdistan Region, Iraq


| Djwar Ali Khasho
Department of Medical Laboratory Sciences, College of Health Sciences, University of Duhok, Kurdistan Region, Iraq


| Nawfal Hussein
Department of Biomedical Sciences, College of Medicine, University of Zakho, Zakho Kurdistan Region, Iraq
نشانی اینترنتی https://acta.tums.ac.ir/index.php/acta/article/view/8270
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