| چکیده انگلیسی مقاله |
Background: Hemodialysis (HD) patients and kidney transplant (KT) recipients are exposed to be infected by blood-borne viruses (BBVs). Current study was conducted to evaluate the prevalence of BBVs in HD and KT patients in the whole Iranian population.
Methods: From Jan 2016 to Dec 2017, 174 hemodialysis and 139 kidney transplant recipients enrolled in this survey. After blood sampling, serum samples were detected for HBV, HCV, HCMV, HIV and HTLV antibodies. Seropositive samples confirmed by Polymerase chain reaction (PCR) method.
Results: Overall, 6 (3.44%) and 3 (2.15%) of hemodialysis-dependent and transplantation patients had evidence of HCV infection, whereas no patients were HIV and HBV positive, two cases (1.14%) of hemodialysis and one case (0.71%) of transplantation patients demonstrated the HTLV-1 infection. 52 (37.4%) of patients received graft were positive for HCMV antibody. In addition, our study showed a co-infection of HCMV with HCV (3 patients, 2.15%) in transplantation patients.
Conclusion: Prevalence of BBVs infection was lower in comparison to the previous studies. The current strict infection control practices in Iran appear to be effective in limiting dialysis and related infections after transplantation. Because BBVs infections constantly occur especially in dialysis and after transplantation units, our data will be useful to build a new strategic plan for the elimination of BBVs infection in kidney therapycenters. |
| نویسندگان مقاله |
| Fatemeh HATATIAN
Inflammation and Inflammatory Disease Research Center, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
| Farzad BABAKHANI
Department of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
| Hoda GUDARZI
Department of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
| Navid MOMENIFAR
Human and Animal Cell Bank, Iranian Biological Resource Center, Academic Center of Education, Culture and Research, Tehran, Iran
| Mehdi NOROUZI
Department of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran AND Research Center for Clinical Virology, Tehran University of Medical Sciences, Tehran, Iran
| Mina SHAFIEIFAR
Department of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
| Ehsan KAKAVANDI
Department of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
| Ahmadreza SADEGHI
Iranian Tissue Bank and Research Center, Tehran University of Medical Sciences, Tehran, Iran
| Hedyeh SHARBATDAR-ALAEI
Department of Microbial Biotechnology, Faculty of Basic Sciences and Advanced Technologies in Biology, University of Science and Culture, Tehran, Iran
| Mohammad FARAHMAND
Department of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
| Maedeh AMIRI-ROUDY
Department of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
| Hamid Reza JAHANTIGH
Department of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
| Mobina MADIHI
Department of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
| Kiandokht BORHANI
Department of Virology, School of Medical Sciences, Tarbiat Modares University, Tehran, Iran
| Mehdi AJORLOO
Hepatitis Research Center, Lorestan University of Medical Sciences, Khorramabad, Iran AND Department of Clinical Laboratory Sciences, School of Allied Medicine, Lorestan University of Medical Sciences, Khorramabad, Iran
| Mojtaba HEDAYAT YAGHOOBI
Department of Infectious Disease, School of Medicine, Alborz University of Medical Sciences, Karaj, Iran
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