این سایت در حال حاضر پشتیبانی نمی شود و امکان دارد داده های نشریات بروز نباشند
Iranian Journal of Microbiology، جلد ۱۳، شماره ۴، صفحات ۵۶۰-۵۶۴
عنوان فارسی
چکیده فارسی مقاله
کلیدواژه‌های فارسی مقاله
عنوان انگلیسی Molecular characterization of healthcare and community-associated methicillin-resistant Staphylococcus aureus using phage open-reading frame typing
چکیده انگلیسی مقاله The polymerase chain reaction-based open reading frame typing (POT) method is a simple and rapid method for the strain-level discrimination of methicillin-resistant Staphylococcus aureus (MRSA). We investigated the molecular characteristics of S. aureus strains by multilocus sequencing typing (MLST) and POT and the profiles of antibiotic resistance and virulence genes of MRSA isolates in a single center of Tokyo, Japan. Five types by MLST and 19 types by POT were detected in the 25 MRSA isolates. ST5 and a POT1 score of 93 were associated with healthcare-associated MRSA, whereas ST8 and a POT1 score of 106 were associated with community-associated MRSA. Each strain evaluated by POT score was completely associated with similar profiles of antibiotic resistance and virulence genes. These data showed that the POT system was a powerful molecular tool for the epidemiological characterization of MRSA isolates, which correlated with the profiles of antibiotic resistance and virulence genes.
کلیدواژه‌های انگلیسی مقاله
نویسندگان مقاله | Takaaki Konuma
Department of Hematology/Oncology, Institute of Medical Sciences, The University of Tokyo, Tokyo, Japan


| Shunsuke Takahashi
Techno Suruga Laboratory Co., Ltd., Shizuoka, Japan


| Masato Suzuki
Department of Laboratory Medicine, Institute of Medical Sciences, The University of Tokyo, Tokyo, Japan


| Arinobu Tojo
Department of Hematology/Oncology, Institute of Medical Sciences, The University of Tokyo, Tokyo, Japan; Department of Laboratory Medicine, Institute of Medical Sciences, The University of Tokyo, Tokyo, Japan
نشانی اینترنتی https://ijm.tums.ac.ir/index.php/ijm/article/view/3125
فایل مقاله فایلی برای مقاله ذخیره نشده است
کد مقاله (doi)
زبان مقاله منتشر شده
موضوعات مقاله منتشر شده
نوع مقاله منتشر شده
برگشت به: صفحه اول پایگاه   |   نسخه مرتبط   |   نشریه مرتبط   |   فهرست نشریات