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Iranian Journal of Blood and Cancer، جلد ۱۲، شماره ۴، صفحات ۱۱۱-۱۲۰
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عنوان انگلیسی Thrombotic Thrombocytopenic Purpura: Diagnosis and Treatment
چکیده انگلیسی مقاله Thrombotic Thrombocytopenic purpura (TTP) is a rare thrombotic microangiopathic disease, associated with thrombocytopenia and hemolytic anemia. It is caused by an enzymatic dysfunction responsible in cleavage of blood clotting factors. In this study we have tried to review the available approaches in diagnoses of the disease as well as treatment strategies. Based on the what the current review has provided, treatment policy depends on accurate diagnosis, it seems that developing a diagnostic and treatment guide for this disease is currently essential. Also, it's necessary to study genetic types of TTP with more details because, hopefully, new techniques of gene therapy open a window to more stable treatments.
کلیدواژه‌های انگلیسی مقاله Thrombotic thrombocytopenic purpura, Diagnosis, Gene therapy
نویسندگان مقاله | Mohammadreza Saeidnia
Department of Hematology, School of Paramedical, Shiraz University of Medical Sciences, Shiraz, Iran


| Faride Nam Avar Jahromi
Department of Hematology, School of Paramedical, Shiraz University of Medical Sciences, Shiraz, Iran


| Elnaz Vaziee
Department of Hematology, School of Paramedical, Shiraz University of Medical Sciences, Shiraz, Iran


| Hossein Dehghani
Department of Hematology, School of Paramedical, Shiraz University of Medical Sciences, Shiraz, Iran


| Amir Mahmoodzade
Medical Biology Research Center, Health Technology Institute, Kermanshah University of Medical Sciences, Kermanshah, Iran


| Gholamhossein Tamaddon
Diagnostic Laboratory Sciences and Technology Research Center, School of Paramedical Sciences, Shiraz University of Medical Sciences, Shiraz, Iran
نشانی اینترنتی http://ijbc.ir/browse.php?a_code=A-10-570-1&slc_lang=en&sid=1
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کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده Adults Hematology & Oncology
نوع مقاله منتشر شده مقاله مروری
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