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Iranian Journal of Toxicology، جلد ۱۵، شماره ۳، صفحات ۱۴۳-۱۵۰
عنوان فارسی بررسی وضعیت مصرف متادون بر اساس آزمایشات سم‌شناسی در فوت‌شدگان به علت سوء مصرف مواد مخدر در سال‌های ۹۶-۱۳۹۴
چکیده فارسی مقاله
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عنوان انگلیسی Evaluation of Methadone Consumption Rate Based on Post-mortem Toxicology Examinations in Cases of Drug-related Deaths in Iran: 2015-2017
چکیده انگلیسی مقاله Background: Given the increasing prevalence of methadone overdose and the growing number of deaths in Iran, the present study was conducted to determine the mortality rate of methadone detected in the cadavers brought to the Forensic Medicine Organization between 2015 and 2017. Methods: This cross-sectional study was performed on 7,486 cases of substance abuse deaths registered in the Forensic Medicine Organization during 2015-2017. In order to investigate the drug abuse, samples collected from the cadavers were initially examined for their drug contents, such as methadone, by standard screening methods and then confirmed by Thin Layer Chromatography (TLC). Using two checklists, the information collected about each cadaver consisted of the identity, autopsy and laboratory data. After data collection, they were entered into the Stata software version 14 MP. Results: The cadavers' mean age was 36.6±12.6 years. Over the 3-year duration of the study, the standardized mortality rate increased from 35 to 39 cases per million per year. Of these cases, 6066 were randomly assigned to toxicology, 50.1% had used methadone one month before their death. Approximately 75% of the methadone abusers had taken another drug simultaneously, mostly morphine or methamphetamine. Conclusion: Considering the relatively high prevalence of methadone detected post-mortem, monitoring for methadone entry into public market and identifying the death-related factors in the drug abusers are considered as significant measures to improve upon the current alarming situation in the Iranian society.  
کلیدواژه‌های انگلیسی مقاله Methadone, Drug abuse, Addiction, Toxicity, Mortality rates
نویسندگان مقاله جلیل حسنی | Jalil Hasani
Department of Nursing, Kashmar School of Nursing, Mashhad University of Medical Sciences, Mashhad, Iran.


سید داوود میرترابی | Davood Mirtorabi
Forensic Medicine Research Center, Forensic Medicine Organization, Tehran, Iran.


محمدرضا قدیرزاده | Mohammad Reza Ghadirzadeh
Forensic Medicine Research Center, Forensic Medicine Organization, Tehran, Iran.


سید امیرحسین مهدوی | Amirhossein Mahdavi
Forensic Medicine Research Center, Forensic Medicine Organization, Tehran, Iran.


سید سعید هاشمی نظری | Saeed Hashemi Nazari
Department of Epidemiology, Safety Promotion and Injury Prevention Research Center, School of Public Health and Safety, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
نشانی اینترنتی http://ijt.arakmu.ac.ir/browse.php?a_code=A-10-786-1&slc_lang=en&sid=1
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