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Iranian Journal of Medical Physics، جلد ۱۸، شماره ۶، صفحات ۴۲۱-۴۲۹

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عنوان انگلیسی Cell Phone and Breast Cancer: The Cell Phone-Generated Pulsed 217Hz ELF Magnetic Field Increases Angiogenesis
چکیده انگلیسی مقاله Introduction: Over the last decades, there has been an increasing trend in using cell phones which are exposing us to Radio-Frequency (RF) and Extremely Low Frequency (ELF) magnetic fields with various known and unknown biological effects. This protective study aimed to investigate the impact of environmental 217 Hz (as an ELF) magnetic fields generated by mobile phones on angiogenesis as an essential factor in tumor growth, in vitro and in vivo. Material and Methods: Magnetic fields with amplitudes of 0.5, 6, 22, 44, 65 & 159 µT were exposed on Human umbilical vein endothelial cells (HUVECs) and proliferation and viability of cells were measured. 3D angiogenesis assay was done by culturing HUVEC-covered microbeads in collagen gel and counting the number of sprouting micro-vessels per microbead. The percent of CD31 positive areas in breast tumor tissues of mice was assessed in the in vivo study. Results: Results showed that some of the applied amplitudes could increase proliferation as well as the viability of HUVECs. Furthermore, 22 and 44 µT magnetic fields could significantly increase the angiogenesis of breast tumors in the mouse. Conclusion: There is a promoting effect from ELF magnetic fields generated by cell phones on the angiogenesis of tumors. It will be helpful if we recommend that cancer patients not to be exposed to cell phones.
کلیدواژه‌های انگلیسی مقاله Magnetic Field, Angiogenesis, Endothelial cells, Mice, Breast Cancer

نویسندگان مقاله | Akram Mahna
Department of Medical Physics, faculty of medicine, Tabriz university of medical sciences, Tabriz, Iran


| Seyed Mohamad Firoozabadi
Department of Medical Physics, School of Medical Sciences, Tarbiat Modares University, Tehran, Iran.


| Amir Atashi
Department of medical laboratory sciences, school of allied medical sciences, Shahroud university of Medical sciences, Shahroud, Iran



نشانی اینترنتی https://ijmp.mums.ac.ir/article_17085.html
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