این سایت در حال حاضر پشتیبانی نمی شود و امکان دارد داده های نشریات بروز نباشند
Iranian Journal of Medical Physics، جلد ۱۸، شماره ۵، صفحات ۳۳۹-۳۴۵
عنوان فارسی
چکیده فارسی مقاله
کلیدواژه‌های فارسی مقاله
عنوان انگلیسی Simultaneous Diffusion and T1 Weighted Contrast Imaging for Human Brain Mapping
چکیده انگلیسی مقاله Introduction: Diffusion tensor imaging (DTI) is typically obtained by echo-planar imaging (EPI) to map the human brain. However, EPI is sensitive to susceptibility effects, requiring elaborate image post-processing. Besides, DTI alone is limited in assessing gray and white matter boundaries of the brain, which has important implications for obtaining accurate images from brain atrophy. This study aimed to design and evaluate simultaneous diffusion and T1 weighting high-resolution imaging for human brain mapping. Material and Methods: The method of T1 weighted three-dimensional Magnetization-prepared rapid gradient-echo (T1w 3D MPRAGE), which is conventionally used for structural brain mapping of gray and white matter, was extended to incorporate diffusion encoding using simulation and experiment to develop high-resolution DTI and T1-weighted human brain data. Results: Theoretical simulations, as well as experimental results from in-vivo human brain studies at 4 Tesla magnetic field strength, showed that the DTI contrast, including fractional anisotropy (FA) and mean diffusivity (MD), incorporated into T1w 3D MPRAGE improves the contrast between gray and white matter sub-structural boundaries. Moreover, diffusion encoding into 3D MPRAGE avoids the inherent image distortions typically seen in EPI-based DTI. Conclusion: This study suggests the capability and effectiveness of the combined DTI weighted 3D MPRAGE and T1 weighted for improving the detection of gray/white matter boundaries in human brain imaging.
کلیدواژه‌های انگلیسی مقاله T1, 3D MPRAGE, diffusion MRI, Contrast, DTI, human brain
نویسندگان مقاله | Marzieh Nezamzadeh
Department of Radiology and Biomedical Imaging, University of California, San Francisco, USA Medical Science School, Tarbiat Modares University, Tehran, Iran


| Norbert Schuff
Department of Radiology and Biomedical Imaging, University of California, San Francisco, USA
نشانی اینترنتی https://ijmp.mums.ac.ir/article_16414.html
فایل مقاله فایلی برای مقاله ذخیره نشده است
کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده
نوع مقاله منتشر شده Original Paper
برگشت به: صفحه اول پایگاه   |   نسخه مرتبط   |   نشریه مرتبط   |   فهرست نشریات