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Caspian Journal of Internal Medicine، جلد ۱۲، شماره ۴، صفحات ۶۰۶-۶۱۲
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عنوان انگلیسی The Association of Serum Lipid Profiles and Dietary Intakes of Vitamin E and Fiber with Psoriasis Severity
چکیده انگلیسی مقاله Background: Dyslipidemia has been reportedly associated with an increased risk of atherosclerosis among psoriatic patients. Dietary intake can be a key factor in the pathophysiology of psoriasis. Herein, we assessed serum lipid profile and dietary intake in psoriatic patients, in comparison with healthy subjects. Methods: In this case-control study, 45 psoriatic patients and 43 healthy controls were evaluated. We estimated the macro/micronutrient intakes and energy, using a food frequency questionnaire (FFQ). Anthropometric parameters and serum levels of triglyceride (TG), high-density lipoproteins (HDL), low-density lipoproteins (LDL), and very low-density lipoproteins were assessed. The case group was categorized by severity measured by PASI score (mild< 10, moderate 10-20, severe >20). Diet plan 6.0 was used to analyze FFQs and data were analyzed in SPSS 16.0, with p< 0.05 considered significant. Results: The case group had markedly higher body mass index (BMI), LDL, and cholesterol and significantly lower HDL compared with controls (p< 0.05). Carbohydrate, energy, fat intakes were significantly higher in cases, while folate, fiber, and vitamin E intakes were significantly lower in the case group, compared with the control group (p< 0.05). BMI, cholesterol, and triglyceride values and dietary intakes of fiber and vitamin E were significantly associated with severity of psoriasis (p< 0.05). Conclusion: Serum lipid profile and dietary intake are substantially important in psoriasis severity. Therefore, close monitoring of lipid profile and BMI during admission and follow-up and dietary modification can improve the severity of psoriasis.
کلیدواژه‌های انگلیسی مقاله psoriasis, FFQ, lipid profile, oxidative stress, BMI, PASI score
نویسندگان مقاله | Mohammad Javad Yazdanpanah
Cutaneous Leishmaniasis Research Center, Mashhad University of Medical Sciences, Mashhad, Iran


| Sadegh Vahabi-Amlashi
Cutaneous Leishmaniasis Research Center, Mashhad University of Medical Sciences, Mashhad, Iran


| Mohsen Nematy
Department of Nutrition and Biochemistry, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran


| Neda Shaelaei
Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran


| Seyed Amir Reza Mohajeri
Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran


| Zahra Tafazzoli
Cutaneous Leishmaniasis Research Center, Mashhad University of Medical Sciences, Mashhad, Iran
نشانی اینترنتی http://caspjim.com/browse.php?a_code=A-10-1773-1&slc_lang=en&sid=1
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کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده Internal
نوع مقاله منتشر شده Original Article
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