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Caspian Journal of Internal Medicine، جلد ۱۲، شماره ۲، صفحات ۱۸۰-۱۸۳
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عنوان انگلیسی The effect of narrowband ultraviolet B phototherapy on serum folate level
چکیده انگلیسی مقاله Background: Narrowband ultraviolet B (NB-UVB) phototherapy has been used as a common treatment for dermatologic diseases such as psoriasis and vitiligo and generally considered a safe form of therapy during pregnancy. Invitro photodegradation of folate after exposure to UVB radiation has been documented but studies on UVB-induced alternation of serum folate level have reported inconsistent results. The aim of this study was to investigate the effect of NB-UVB radiation on serum folate level. Methods: In this study, serum folate levels were evaluated in patients at baseline and after 30 sessions of NB-UVB irradiation. Results: Twenty patients completed the study: 10 psoriasis, 7 vitiligo and 3 mycosis fungoides (patch stage). Mean serum folate level had significantly decreased from 2.76±0.59 ng/ml at baseline to 1.34±0.15 ng/ml after 30 sessions. (Mean NB-UVB cumulative dose 40.35±16.80 j/cm2, P=0.001). Conclusion: Serum folate levels may decrease after long-term NB-UVB phototherapy in patients with skin disorders.
کلیدواژه‌های انگلیسی مقاله narrowband ultraviolet B phototherapy, folate, psoriasis, vitiligo
نویسندگان مقاله | Azar Shirzadian kebria
Department of Dermatology, Yahyanejad Hospital, Babol University of Medical Sciences, Babol, Iran


| Meghdad Hosseini
Babol University of Medical Sciences, Babol, Iran


| Sorayya khafri
Infertility and Reproductive Health Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran
نشانی اینترنتی http://caspjim.com/browse.php?a_code=A-10-1811-1&slc_lang=en&sid=1
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کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده Dermathology
نوع مقاله منتشر شده Original Article
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