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Middle East Journal of Cancer، جلد ۱۳، شماره ۱، صفحات ۱۴۳-۱۴۹
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عنوان انگلیسی Risk Estimation of Thyroid Cancer for Children Undergoing Brain CT Examinations
چکیده انگلیسی مقاله Background: Despite significant diagnosis benefits, the usage of ionizing radiation is not risk-free. The aim of this study was to determine the risk of thyroid cancer for children who exposed to brain computed tomography (CT) scan. Method: In this cross-sectional study, 90 patients under 20 years of age who underwent brain CT-scan were selected. Parameters such as age, sex, imaging technique, imaging characteristics, and thyroid absorbed dose were considered. We used SPSS software, version 21, at 95% confidence interval to analyze the absorbed dose and risk for each individual. Results: The mean and standard deviation of absorbed doses for girls and boys for the spiral technique were 3.954±0.393 and 4.72±0.000 mGy, and in sequential technique, were 2.282±0.461 and 1.985±0.431 mGy, respectively. The mean and standard deviation of the absorbed doses in < 5 years age group were 5.65±2.00, 3.03±1.34 in 6 to 10 years, 2.63±0.98 in 11 to 15 years, and in 16 to 20 years were 2.57±1.04 mGy (P < 0.001). There was a significant negative correlation between the absorbed dose and field dimensions (r = -0.604, P < 0.001) and slice thickness (r = -0.777, P < 0.001). The mean and standard deviation of Lifetime risk for thyroid cancer induction (×105) in < 5 years age group in spiral technique was 158.79±322.50 for female subjects and 16.5±42.90 for male patients, which was significantly more than those of other groups and techniques (P < 0.001). Conclusion: The rate of thyroid absorbed dose during brain CT-scan was found to be noticeable, especially in spiral CT imaging, for female patients < 5 years. Based on our results, it was associated with an increased risk of thyroid cancer in this age group.
کلیدواژه‌های انگلیسی مقاله Computed Tomography, Thyroid Dose, Cancer Risk, children
نویسندگان مقاله Morteza Majidi Ata |
School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran

Abbas Moradi |
Department of Social Medicine, School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran

Farideh Gharekhanloo |
Department of Radiology, School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran

Safoora Nikzad |
Department of Medical Physics, School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran

نشانی اینترنتی https://mejc.sums.ac.ir/article_47569_28209376fef5238c95b474fa6ceb3d72.pdf
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