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Middle East Journal of Cancer، جلد ۱۲، شماره ۲، صفحات ۳۰۲-۳۰۹
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عنوان انگلیسی Survival Rate of Non-Epithelial Ovarian Tumors in Iran
چکیده انگلیسی مقاله Background: The aim of this study was to estimate the overall survival (OS) and relapse free survival (RFS) of the non-epithelial ovarian tumors (NEOTs) of ovarian germ cell tumors (OGCT) and ovarian sex cord tumors (OSCT) in Iranian women; we also evaluated the relative prognostic factors. Method: In this retrospective study, we screened the documents of all the women diagnosed with OGCTs and OSCTs from 2012 to 2019. We further assessed the OS, RFS, and different prognostic factors. Results: A statistically significant association existed between RFS and stage of the disease at diagnosis in OSCTs group by univariate analysis and multivariate analysis (HR: 0.25 (95% CI (0.08-0.78), P=0.01) and multivariate analysis (HR: 0.27 (95% CI (0.08-0.97), P=0.04), respectively. The kaplan-meier analysis and the Log Rrank (Mantel-Cox) showed a statistically significant relationship between the stage at diagnosis and RFS in OGCT group (P=0.042). RFS was 96% for OGCT patients, and 92.7% for OSCT patients. During the follow-up, only one patient passed away in the dysgerminoma group; the OS rate was 98% for OGCT patients, and 100% for OSCT patients. Conclusion: The OS and RFS obtained in this study confirmed that the ovarian germ cell and sex cord malignancies were among the highly treatable solid tumors. Stage can be proposed as the main prognostic factor; also, larger series of studies are needed for detecting the prognostic significance of serum markers.
کلیدواژه‌های انگلیسی مقاله Survival, Ovarian Cancer, Germ cell ovarian tumor, Sex cord ovarian tumor
نویسندگان مقاله Somayeh Bolandi |
Department of Obstetrics and Gynecology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran

Maryam Nakhaee |
Department of Obstetrics and Gynecology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran

Laya Shirinzadeh |
Department of Obstetrics and Gynecology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran

Amir Hossein Jafarian |
Department of Pathology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran

Behrooz Davachi |
Department of Radiology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran

Tahereh Zavari |
Department of Obstetrics and Gynecology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran

Fatemeh Shirzadeh |
Department of Obstetrics and Gynecology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran

Zohreh Yousefi |
Department of Obstetrics and Gynecology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran

نشانی اینترنتی https://mejc.sums.ac.ir/article_46999_aec5cd080438c027ca302f6ebd0b37b3.pdf
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