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Basic and Clinical Neuroscience، جلد ۱۲، شماره ۲، صفحات ۱۶۳-۱۷۶
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چکیده فارسی مقاله
کلیدواژه‌های فارسی مقاله
عنوان انگلیسی Presurgical Language Mapping in Patients With Intractable Epilepsy: A Review Study
چکیده انگلیسی مقاله Introduction: about 20% to 30% of patients with epilepsy are diagnosed with drug-resistant epilepsy and one third of these are candidates for epilepsy surgery. Surgical resection of the epileptogenic tissue is a well-established method for treating patients with intractable focal epilepsy. Determining language laterality and locality is an important part of a comprehensive epilepsy program before surgery. Functional Magnetic Resonance Imaging (fMRI) has been increasingly employed as a non-invasive alternative method for the Wada test and cortical stimulation. Sensitive and accurate language tasks are essential for any reliable fMRI mapping.  Methods: The present study reviews the methods of presurgical fMRI language mapping and their dedicated fMRI tasks, specifically for patients with epilepsy. Results: Different language tasks including verbal fluency are used in fMRI to determine language laterality and locality in different languages such as Persian. there are some considerations including the language materials and technical protocols for task design that all presurgical teams should take into consideration. Conclusion: Accurate presurgical language mapping is very important to preserve patients language after surgery. This review was the first part of a project for designing standard tasks in Persian to help precise presurgical evaluation and in Iranian PWFIE. 
کلیدواژه‌های انگلیسی مقاله Epilepsy, Brain mapping, Language, Functional Magnetic Resonance Imaging (fMRI), Persian
نویسندگان مقاله | Mahdieh Karami
Institute for Cognitive Science Studies (ICSS), Tehran, Iran.


| Jafar Mehvari Habibabadi
Isfahan Neuroscience Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.


| Reza Nilipour
Department of Speech Therapy, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran.


| Majid Barekatain
Center for Neuroscience and Behavioral Health, Children’s National Medical Center, George Washington University, Washington, D.C. USA.


| William D. Gaillard
Center for Neuroscience and Behavioral Health, Children’s National Medical Center, George Washington University, Washington, D.C. USA.


| Hamid Soltanian-Zadeh
Departments of Communication, School of Electrical and Computer Engineering, University of Tehran, Tehran, Iran.
نشانی اینترنتی http://bcn.iums.ac.ir/browse.php?a_code=A-10-2053-1&slc_lang=en&sid=1
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کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده Clinical Neuroscience
نوع مقاله منتشر شده Review
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